Congenital Tuberculosis: A Diagnostic Challenge that Stems from the Mother  

作　　者：Paula Rincon Sara Vallejo Tamayo Juan Gonzalo Mesa Alejandro Diaz Paula Rincon;Sara Vallejo Tamayo;Juan Gonzalo Mesa;Alejandro Diaz(Department of Pediatrics, CES University, Medelln, Colombia;Department of Pediatrics and Infectious Diseases, CES University, Medelln, Colombia)

机构地区：[1]Department of Pediatrics, CES University, Medelln, Colombia [2]Department of Pediatrics and Infectious Diseases, CES University, Medelln, Colombia

出　　处：《Case Reports in Clinical Medicine》2024年第12期512-519,共8页临床医学病理报告(英文)

摘　　要：Tuberculosis (TB) is an age-old disease with a high prevalence worldwide;however, congenital presentation is infrequent and is rarely described in the literature. The incidence of congenital TB is not well-established, with fewer than 400 cases published in scientific literature. Fetal transmission rates can vary between 0 - 16%, with transmission being exceptional with maternal pulmonary TB, especially when the mother has received appropriate treatment, while more common from genital or miliary/disseminated TB. We present the case of a 31-week preterm newborn with a mother’s history of miliary TB with meningeal involvement diagnosed before delivery but with poor adherence to pharmacological treatment. Congenital TB was diagnosed as early as the second day of life, leading to a prompt initiation of therapy.Tuberculosis (TB) is an age-old disease with a high prevalence worldwide;however, congenital presentation is infrequent and is rarely described in the literature. The incidence of congenital TB is not well-established, with fewer than 400 cases published in scientific literature. Fetal transmission rates can vary between 0 - 16%, with transmission being exceptional with maternal pulmonary TB, especially when the mother has received appropriate treatment, while more common from genital or miliary/disseminated TB. We present the case of a 31-week preterm newborn with a mother’s history of miliary TB with meningeal involvement diagnosed before delivery but with poor adherence to pharmacological treatment. Congenital TB was diagnosed as early as the second day of life, leading to a prompt initiation of therapy.

关 键 词：Congenital Tuberculosis NEWBORN TRANSMISSION 

分 类 号：H31[语言文字—英语]