Impact of a physical activity program on plasma concentrations of adiponectin, leptin and ghrelin in overweight and obese schoolchildren: A randomized controlled trial  

作　　者：Andre Everton de Freitas Joel Alves Lamounier Danusa Dias Soares Thiago Henrique de Oliveira Debora Romualdo Lacerda Joyce Batista Andrade Flavia Komatsuzaki Leida Maria Botion Adaliene Versiani Matos Ferreira Camilo Adalto Mariano da Silva Dilermando Fazito Rezende 

机构地区：[1]Graduate Program in Child and Teenager Health,Medicine School,Federal University of Minas Gerais,Belo Horizonte,Brazil [2]Faculty of Health and Human Ecology,Medicine School,Vespasiano,Brazil [3]Graduate Program in Health Sciences,Medicine School,Federal University of Sao Joao Del Rei,Campus Midwest,Divinopolis,Brazil [4]Laboratory of Exercise Physiology,Federal University of Minas Gerais,Belo Horizonte,Brazil [5]Laboratory of Metabolism,Federal University of Minas Gerais,Belo Horizonte,Brazil [6]School of Nursing,Federal University of Minas Gerais,Belo Horizonte,Brazil [7]School of Nutrition,Federal University of Ouro Preto,Ouro Preto,Brazil [8]Faculty of Medicine Barbacena,Barbacena,Brazil

出　　处：《Health》2013年第11期1819-1828,共10页健康（英文）

摘　　要：Introduction: Child obesity has important consequences on the child’s health and is related to the risk of developing chronic diseases. That brings up the need for research assessing the impact of obesity-and overweight-reduction programs with close attention to methodology aspects and precise indicators of the impact of such programs. Goal: Assessing the impact of a physical activity program on the plasma concentrations of adiponectin, leptin, and ghrelin in overweight and obese schoolchildren. Methods: Randomized controlled trial, double-blind, with 6-to 9-year-old overweight and obese school-children. A sample of 79 schoolchildren randomly distributed into control and intervention groups was subjected to a physical activity program. The levels of adiponectin, leptin, ghrelin, body mass index, body fat percentage, anthropometry, lipid profile and glycemia were evaluated. The program’s impact was assessed through multivariate linear regression models. Result: When comparing the groups, a significant difference was found for adiponectin, which shows an increase in the proportion of subjects with higher adiponectin concentrations for the intervention group and a reduction in body mass index and body fat percentage. Conclusion: The impact of the intervention program was positive in increasing adiponectin levels associated with a reduction in body mass index and body fat percentage.Introduction: Child obesity has important consequences on the child’s health and is related to the risk of developing chronic diseases. That brings up the need for research assessing the impact of obesity-and overweight-reduction programs with close attention to methodology aspects and precise indicators of the impact of such programs. Goal: Assessing the impact of a physical activity program on the plasma concentrations of adiponectin, leptin, and ghrelin in overweight and obese schoolchildren. Methods: Randomized controlled trial, double-blind, with 6-to 9-year-old overweight and obese school-children. A sample of 79 schoolchildren randomly distributed into control and intervention groups was subjected to a physical activity program. The levels of adiponectin, leptin, ghrelin, body mass index, body fat percentage, anthropometry, lipid profile and glycemia were evaluated. The program’s impact was assessed through multivariate linear regression models. Result: When comparing the groups, a significant difference was found for adiponectin, which shows an increase in the proportion of subjects with higher adiponectin concentrations for the intervention group and a reduction in body mass index and body fat percentage. Conclusion: The impact of the intervention program was positive in increasing adiponectin levels associated with a reduction in body mass index and body fat percentage.

关 键 词：Obesity OVERWEIGHT SCHOOLCHILDREN Physical Activity Adipocitokines 

分 类 号：R5[医药卫生—内科学]