Updates in the Diagnosis of Gestational Trophoblast Disease  

Updates in the Diagnosis of Gestational Trophoblast Disease

在线阅读下载全文

作  者:Maira de Lima Oliveira Mota Marcela Curvêllo Beltrão Elizabeth Bacha Eduardo Fonseca Mascarenhas Filho Maísa Mendonça de Jesus Nelson Henriky Felix Mascarenhas Tallys Leandro Barbosa da Silva Maria Fernanda Telles Pires de Souza Victoria de Oliveira Carmo Borges Séfora Maria Fragoso Braga Maira de Lima Oliveira Mota;Marcela Curvêllo Beltrão;Elizabeth Bacha;Eduardo Fonseca Mascarenhas Filho;Maísa Mendonça de Jesus;Nelson Henriky Felix Mascarenhas;Tallys Leandro Barbosa da Silva;Maria Fernanda Telles Pires de Souza;Victoria de Oliveira Carmo Borges;Séfora Maria Fragoso Braga(Centro Universitário Tiradentes (UNIT), Maceió, Brasil;Estácio de Juazeiro do Norte (FMJ), Ceará, Brasil;Universidade Federal de Alagoas (UFAL), Maceió, Brasil;São Leopoldo Mandic, Campinas, Brasil;Hospital Regional de Arapiraca, Arapiraca, Brasil)

机构地区:[1]Centro Universitário Tiradentes (UNIT), Maceió, Brasil [2]Estácio de Juazeiro do Norte (FMJ), Ceará, Brasil [3]Universidade Federal de Alagoas (UFAL), Maceió, Brasil [4]Sã o Leopoldo Mandic, Campinas, Brasil [5]Hospital Regional de Arapiraca, Arapiraca, Brasil

出  处:《Health》2023年第1期48-58,共11页健康(英文)

摘  要:GTD (Gestational Trophoblastic Disease) is a pathology that encompasses benign and malignant clinical forms, affects women of childbearing age, has a variable incidence and is more frequent in developing or underdeveloped countries, colliding with the economic barrier. The frequent absence of clear protocols and guidelines for the correct diagnosis of the pathology results in inadequate classification, imprecise treatment and failed post-therapeutic observation, increasing the risk of relapses, morbidity and mortality. The present study aims to point out updated national and international practice protocols of diagnosis of GTD, through an integrative review. Seven articles were selected and it was observed that the main international reference centers are agreed with the management suggested by the IFGO (International Federation of Gynecology and Obstetrics), being the conduct in the Hydatidiform Mole (HM): evacuation by suction and curettage under ultrasound guidance, followed by hCG monitoring every 1 - 2 weeks until normalized (usually one month for Partial Hydatidiform Mole six months for Complete Hydatidiform Mole and one year for Gestational Trophoblastic Neoplasia). Unfortunately, regarding the diagnosis of MH, the guidelines of some countries show the absence or difficulty of access to the karyotype test and ploid p57 or pelvic ultrasound accompanying the uterine curettage, contrary to what is proposed by the IFGO guideline. Establishing and complying with consistent guidelines can improve patient care, with early diagnosis of the pathology and its complications, reducing the rate of recurrence, morbidity and mortality, especially in less developed countries.GTD (Gestational Trophoblastic Disease) is a pathology that encompasses benign and malignant clinical forms, affects women of childbearing age, has a variable incidence and is more frequent in developing or underdeveloped countries, colliding with the economic barrier. The frequent absence of clear protocols and guidelines for the correct diagnosis of the pathology results in inadequate classification, imprecise treatment and failed post-therapeutic observation, increasing the risk of relapses, morbidity and mortality. The present study aims to point out updated national and international practice protocols of diagnosis of GTD, through an integrative review. Seven articles were selected and it was observed that the main international reference centers are agreed with the management suggested by the IFGO (International Federation of Gynecology and Obstetrics), being the conduct in the Hydatidiform Mole (HM): evacuation by suction and curettage under ultrasound guidance, followed by hCG monitoring every 1 - 2 weeks until normalized (usually one month for Partial Hydatidiform Mole six months for Complete Hydatidiform Mole and one year for Gestational Trophoblastic Neoplasia). Unfortunately, regarding the diagnosis of MH, the guidelines of some countries show the absence or difficulty of access to the karyotype test and ploid p57 or pelvic ultrasound accompanying the uterine curettage, contrary to what is proposed by the IFGO guideline. Establishing and complying with consistent guidelines can improve patient care, with early diagnosis of the pathology and its complications, reducing the rate of recurrence, morbidity and mortality, especially in less developed countries.

关 键 词:DIAGNOSIS Gestational Trophoblastic Disease UPDATES 

分 类 号:R71[医药卫生—妇产科学]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象