Faster Healing Process by Sparing Intramural Myoma’s Pseudocapsule during Laparoscopic Myomectomy Compared with Removing It during Open Myomectomy  

作　　者：Athanasios Zikopoulos Yannis Prapas Maria Paraskevaidi Charalampos Siristatidis Apostolia Galani Orestis Tsonis Minas Paschopoulos Konstantinos Zikopoulos Efstratios Kolibianakis Athanasios Zikopoulos;Yannis Prapas;Maria Paraskevaidi;Charalampos Siristatidis;Apostolia Galani;Orestis Tsonis;Minas Paschopoulos;Konstantinos Zikopoulos;Efstratios Kolibianakis(Department of Obstetrics and Gynaecology, Royal Cornwall Hospital, Cornwall, UK;IAKENTRO, Infertility Treatment Centre, Thessaloniki, Greece;Institute of Reproductive and Developmental Biology, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK;Second Department of Obstetrics and Gynaecology/Assisted Reproduction Unit, Faculty of Medicine, Aretaieion Hospital, National and Kapodistrian University of Athens, Athens, Greece;Department of Obstetrics and Gynaecology, Royal Preston Hospital, Preston, UK;Department of Obstetrics and Gynaecology/Assisted Reproduction, Faculty of Medicine, University of Ioannina, Ioannina, Greece;Unit for Human Reproduction, 1st Department of Obstetrics and Gynaecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece)

机构地区：[1]Department of Obstetrics and Gynaecology, Royal Cornwall Hospital, Cornwall, UK [2]IAKENTRO, Infertility Treatment Centre, Thessaloniki, Greece [3]Institute of Reproductive and Developmental Biology, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK [4]Second Department of Obstetrics and Gynaecology/Assisted Reproduction Unit, Faculty of Medicine, Aretaieion Hospital, National and Kapodistrian University of Athens, Athens, Greece [5]Department of Obstetrics and Gynaecology, Royal Preston Hospital, Preston, UK [6]Department of Obstetrics and Gynaecology/Assisted Reproduction, Faculty of Medicine, University of Ioannina, Ioannina, Greece [7]Unit for Human Reproduction, 1st Department of Obstetrics and Gynaecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece

出　　处：《International Journal of Clinical Medicine》2021年第10期424-432,共9页临床医学国际期刊（英文）

摘　　要：Uterine fibroids are the most common benign tumours in the reproductive system. They are proliferations of smooth muscle cells of the myometrium containing a large quantity of extracellular matrix and they are surrounded by a pseudo capsule of compressed areolar tissue and smooth muscle cells. They can cause various symptoms such as menorrhage, pain and infertility and therefore they can be a traumatic experience for several women. The treatment of choice is myomectomy. In the past, myomectomy was performed by relatively atraumatic techniques, which involved stretching the myoma from its pseudocapsule to extract the fibroid directly from the surrounding fibromuscular tissue, breaking up the fibrous bridge. Modern laparoscopic intracapsular myomectomy (LIM), however, leaves the fibrovascular network surrounding the myoma (namely the “fibroid neurovascular bundle”) intact which reduces the bleeding and/or uterine musculature trauma, and spares the neuropeptide fibers of the pseudocapsule. In this observational study, we compare the two techniques-laparoscopic intracapsular myomectomy (LIM) and conventional abdominal myomectomy (CAM) regarding the longterm uterine healing and a significantly faster healing process of the uterine incision was achieved by LIM compared to CAM.Uterine fibroids are the most common benign tumours in the reproductive system. They are proliferations of smooth muscle cells of the myometrium containing a large quantity of extracellular matrix and they are surrounded by a pseudo capsule of compressed areolar tissue and smooth muscle cells. They can cause various symptoms such as menorrhage, pain and infertility and therefore they can be a traumatic experience for several women. The treatment of choice is myomectomy. In the past, myomectomy was performed by relatively atraumatic techniques, which involved stretching the myoma from its pseudocapsule to extract the fibroid directly from the surrounding fibromuscular tissue, breaking up the fibrous bridge. Modern laparoscopic intracapsular myomectomy (LIM), however, leaves the fibrovascular network surrounding the myoma (namely the “fibroid neurovascular bundle”) intact which reduces the bleeding and/or uterine musculature trauma, and spares the neuropeptide fibers of the pseudocapsule. In this observational study, we compare the two techniques-laparoscopic intracapsular myomectomy (LIM) and conventional abdominal myomectomy (CAM) regarding the longterm uterine healing and a significantly faster healing process of the uterine incision was achieved by LIM compared to CAM.

关 键 词：MYOMECTOMY Laparoscopic Intracapsular Myomectomy HEALING 

分 类 号：O55[理学—热学与物质分子运动论]