Factors Associated with Children’s Death Due to Congenital Heart Disease in Two National Hospitals of Niamey  

作　　者：M’baye Salissou Seck M’baye Samaila Aboubacar Kamaye Moumouni Abdou Siddo Hadjara Garba Moumouni Adehossi Irene Abdoul Djafar Mamoudou Tsague Kengni Hermann Nestor Amadou Douada Issoufou Alzouma Maliki Abdoulaye Moctar Mianroh Hybi Langtar Laouan Hamidou Ngo Yon Laurence Carole Guindo Aissata Ndobo Valerine Siddikatou Djibrilla Touré Ali M’baye Salissou Seck M’baye;Samaila Aboubacar;Kamaye Moumouni;Abdou Siddo Hadjara;Garba Moumouni;Adehossi Irene;Abdoul Djafar Mamoudou;Tsague Kengni Hermann Nestor;Amadou Douada;Issoufou Alzouma;Maliki Abdoulaye Moctar;Mianroh Hybi Langtar;Laouan Hamidou;Ngo Yon Laurence Carole;Guindo Aissata;Ndobo Valerine;Siddikatou Djibrilla;Touré Ali(Faculty of Health Sciences, Andr Salifou University of Zinder, Zinder, Niger;Faculty of Science of Health, Abdou Moumouni University, Niamey, Niger;Faculty of Medicine and Science Pharmaceuticals, University of Douala, Douala, Cameroon;General Reference Hospital in Niamey, Niamey, Niger;Pedagogical and Research Unit, Mohamed V University, Rabat, Morocco;Faculty of Health Sciences, Adam Barka University of Abeche, Abeche, Chad;Faculty of Health Sciences, Dan Dicko Dankoulodo University of Maradi, Maradi, Niger;Point G Hospital Center, Bamako, Mali;Faculty of Medicine and Biomedical Sciences of Yaound 1, Yaound, Cameroon;Faculty of Health Sciences, University of Buea, Buea, Cameroon)

机构地区：[1]Faculty of Health Sciences, Andr Salifou University of Zinder, Zinder, Niger [2]Faculty of Science of Health, Abdou Moumouni University, Niamey, Niger [3]Faculty of Medicine and Science Pharmaceuticals, University of Douala, Douala, Cameroon [4]General Reference Hospital in Niamey, Niamey, Niger [5]Pedagogical and Research Unit, Mohamed V University, Rabat, Morocco [6]Faculty of Health Sciences, Adam Barka University of Abeche, Abeche, Chad [7]Faculty of Health Sciences, Dan Dicko Dankoulodo University of Maradi, Maradi, Niger [8]Point G Hospital Center, Bamako, Mali [9]Faculty of Medicine and Biomedical Sciences of Yaound 1, Yaound, Cameroon [10]Faculty of Health Sciences, University of Buea, Buea, Cameroon

出　　处：《International Journal of Clinical Medicine》2024年第11期502-511,共10页临床医学国际期刊（英文）

摘　　要：Introduction: Congenital heart disease is a major cause of children’s death. In Niger, despite the frequency of these pathologies, very few studies have been carried out on associated mortality in a paediatric environment. The objective of this work was to look for the risk factors of children with congenital heart disease’s death in Niamey. Patients and Method: It is about a cross-sectional study for descriptive and analytical purposes in children aged from 0 to 15 years. Carriers of congenital heart disease followed from January 2016 to July 2021 in two national hospitals in Niamey. The variable depends and the main ante was the occurrence of deaths (yes or no). The explanatory variables were related to the characteristics of the patients, the type of heart disease and management among others. Chi’s tests2 Pearson’s or Fischer’s exact test were used (P Results: During the period of the research, 514 cases of congenital heart disease were studied, including 132 deaths (25.68%). The average age of patients was 14.64 months [10 days - 15 years]. The sex ratio was 1.08. The most common reason for consultation was respiratory distress that was found in 74.90% of patients. Interventricular communication (IVC) and intear communication (CIA) were the most found type of heart disease with 36.53% and 20.44% of cases respectively. Only 9.54% of patients (n = 48) had received surgical management. The risk factors associated with mortality were pulmonary arterial hypertension (54.17%), pulmonary disease (44.55%) and the presence of anemia (63.16%) [OR > 1;p Conclusion: Congenital heart diseases remain an important cause of death among children in Niger. The pulmonary arterial hypertension and the associated comorbidities such as broncho-pulmonary diseases were the main associated factors. In the meantime, an optimal technical management of these factors will help to reduce this mortality.Introduction: Congenital heart disease is a major cause of children’s death. In Niger, despite the frequency of these pathologies, very few studies have been carried out on associated mortality in a paediatric environment. The objective of this work was to look for the risk factors of children with congenital heart disease’s death in Niamey. Patients and Method: It is about a cross-sectional study for descriptive and analytical purposes in children aged from 0 to 15 years. Carriers of congenital heart disease followed from January 2016 to July 2021 in two national hospitals in Niamey. The variable depends and the main ante was the occurrence of deaths (yes or no). The explanatory variables were related to the characteristics of the patients, the type of heart disease and management among others. Chi’s tests2 Pearson’s or Fischer’s exact test were used (P Results: During the period of the research, 514 cases of congenital heart disease were studied, including 132 deaths (25.68%). The average age of patients was 14.64 months [10 days - 15 years]. The sex ratio was 1.08. The most common reason for consultation was respiratory distress that was found in 74.90% of patients. Interventricular communication (IVC) and intear communication (CIA) were the most found type of heart disease with 36.53% and 20.44% of cases respectively. Only 9.54% of patients (n = 48) had received surgical management. The risk factors associated with mortality were pulmonary arterial hypertension (54.17%), pulmonary disease (44.55%) and the presence of anemia (63.16%) [OR > 1;p Conclusion: Congenital heart diseases remain an important cause of death among children in Niger. The pulmonary arterial hypertension and the associated comorbidities such as broncho-pulmonary diseases were the main associated factors. In the meantime, an optimal technical management of these factors will help to reduce this mortality.

关 键 词：Congenital Heart Disease Associated Factors to Lethality NIGER 

分 类 号：R54[医药卫生—心血管疾病]