Prevalence and Risk Factors Associated with Tungiasis among School-Aged Children in the City of Port Gentil, Ogooué-Maritime Province, Gabon in Central Africa  

作　　者：Thiéry Ndong Mba Cédric Sima Obiang Hilaire Moundounga Kenguele Arnaud Brice Pambo-Pambo Adelaïde Niéguitsila Armel Obiandong Eyivono Ulrich Nzamba Cyrille Bisseye Patrick Mickala Thiéry Ndong Mba;Cédric Sima Obiang;Hilaire Moundounga Kenguele;Arnaud Brice Pambo-Pambo;Adelaïde Niéguitsila;Armel Obiandong Eyivono;Ulrich Nzamba;Cyrille Bisseye;Patrick Mickala(Laboratory of Molecular and Cellular Biology (LABMC), University of Science and Technology of Masuku (USTM), Franceville, Gabon;Laboratory of Research in Biochemistry (LAREBIO), University of Sciences and Techniques of Masuku (USTM), Franceville, Gabon;Laboratory of Animal Physiology, University of Science and Technology of Masuku (USTM), Franceville, Gabon;Laboratory of Multidisciplinary Research in Environment (LARME), University of Science and Technology of Masuku (USTM), Franceville, Gabon)

机构地区：[1]Laboratory of Molecular and Cellular Biology (LABMC), University of Science and Technology of Masuku (USTM), Franceville, Gabon [2]Laboratory of Research in Biochemistry (LAREBIO), University of Sciences and Techniques of Masuku (USTM), Franceville, Gabon [3]Laboratory of Animal Physiology, University of Science and Technology of Masuku (USTM), Franceville, Gabon [4]Laboratory of Multidisciplinary Research in Environment (LARME), University of Science and Technology of Masuku (USTM), Franceville, Gabon

出　　处：《Journal of Biosciences and Medicines》2022年第11期176-191,共16页生物科学与医学（英文）

摘　　要：Background: Tungiasis is a skin infestation caused by the female sand flea called Tunga penetrans. Associated with a significant morbidity, this ectoparasite is present in all tropical regions, such as Gabon. Unfortunately, in this country, no study has ever been undertaken on this disease. However, in both urban and rural areas of this country, it causes disfigurement and mutilation of the feet or hands in infested persons, and is sometimes responsible for the school dropout of many children. It is in this context that this timely and relevant research was conducted to assess the prevalence and risk factors associated with Tungiasis in school-aged children in the city of Port Gentil, Ogooué-Maritime province, Gabon in Central Africa. Materials and Methods: This prospective and cross-sectional study took place from May 22 to August 18, 2022, in two popular and underprivileged neighborhoods of the city of Port Gentil. It consisted of a physical diagnosis of the participants, and with the help of a questionnaire submitted to their parents/guardians, numerous data were collected. Entered into an Excel 2016 spreadsheet, the data were exported to the R software in its R Commander interface, for two types of analyses. A univariate and a multivariate analysis, using logistic regression, first on socio-demographic characteristics and then on habitual and environmental behavioral characteristics, was performed and the variables in this analysis reported odds ratios and their 95% confidence intervals. The results were statistically significant at p Results: A total of 637 school-aged children with a mean age of 12.73 years and a standard deviation of 5.44, were registered and examined for this study. Among them, Tunga penetrans infestation was found in 242 children, indicating an overall prevalence of 37.99% (95% CI [0.34 - 0.41]). Univariate and multivariate analyses, using logistic regression, first according to socio-demographic characteristics and then according to risk factors indicated that, the age groups of 5 to 9Background: Tungiasis is a skin infestation caused by the female sand flea called Tunga penetrans. Associated with a significant morbidity, this ectoparasite is present in all tropical regions, such as Gabon. Unfortunately, in this country, no study has ever been undertaken on this disease. However, in both urban and rural areas of this country, it causes disfigurement and mutilation of the feet or hands in infested persons, and is sometimes responsible for the school dropout of many children. It is in this context that this timely and relevant research was conducted to assess the prevalence and risk factors associated with Tungiasis in school-aged children in the city of Port Gentil, Ogooué-Maritime province, Gabon in Central Africa. Materials and Methods: This prospective and cross-sectional study took place from May 22 to August 18, 2022, in two popular and underprivileged neighborhoods of the city of Port Gentil. It consisted of a physical diagnosis of the participants, and with the help of a questionnaire submitted to their parents/guardians, numerous data were collected. Entered into an Excel 2016 spreadsheet, the data were exported to the R software in its R Commander interface, for two types of analyses. A univariate and a multivariate analysis, using logistic regression, first on socio-demographic characteristics and then on habitual and environmental behavioral characteristics, was performed and the variables in this analysis reported odds ratios and their 95% confidence intervals. The results were statistically significant at p Results: A total of 637 school-aged children with a mean age of 12.73 years and a standard deviation of 5.44, were registered and examined for this study. Among them, Tunga penetrans infestation was found in 242 children, indicating an overall prevalence of 37.99% (95% CI [0.34 - 0.41]). Univariate and multivariate analyses, using logistic regression, first according to socio-demographic characteristics and then according to risk factors indicated that, the age groups of 5 to 9

关 键 词：PREVALENCE Risk Factors TUNGIASIS School-Aged Children Port Gentil Ogooué-Maritime GABON 

分 类 号：F42[经济管理—产业经济]