Steroidogenic Effects and Phytochemical Profile of Aqueous Extract of Tetracarpidium conophorum (Mull. Arg.) & Hutch Kernels in Male Rats  

作　　者：Herman Akassa Bonaventure Max Lazare Peneme Constantin Moukouma Dieu-Merci Bevel Gallo Mongo Rachie Osandze Arnaud Wilfrid Etou Ossibi Ange Antoine Abena Herman Akassa;Bonaventure Max Lazare Peneme;Constantin Moukouma;Dieu-Merci Bevel Gallo Mongo;Rachie Osandze;Arnaud Wilfrid Etou Ossibi;Ange Antoine Abena(Laboratory of Biochemistry and Pharmacology, Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Republic of the Congo;Laboratory of Animal Physiology, Faculty of Science and Technology, Marien Ngouabi University, Brazzaville, Republic of the Congo;Departement of Pharmacopeia and Traditional Medicine, National Institute for Research in Health Sciences (IRSSA), Brazzaville, Republic of the Congo;Chemistry Unit of the Plant and Life, Faculty of the Sciences and Techniques, Marien Ngouabi University, Brazzaville, Republic of the Congo;Faculty of Applied Sciences, Denis Sassou Nguesso University, Kintelé, Republic of the Congo)

机构地区：[1]Laboratory of Biochemistry and Pharmacology, Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Republic of the Congo [2]Laboratory of Animal Physiology, Faculty of Science and Technology, Marien Ngouabi University, Brazzaville, Republic of the Congo [3]Departement of Pharmacopeia and Traditional Medicine, National Institute for Research in Health Sciences (IRSSA), Brazzaville, Republic of the Congo [4]Chemistry Unit of the Plant and Life, Faculty of the Sciences and Techniques, Marien Ngouabi University, Brazzaville, Republic of the Congo [5]Faculty of Applied Sciences, Denis Sassou Nguesso University, Kintelé, Republic of the Congo

出　　处：《Journal of Biosciences and Medicines》2023年第10期156-167,共12页生物科学与医学（英文）

摘　　要：The main aim of this study was to evaluate the steroidogenic effects and phytochemical profile of aqueous extract of Tetracarpidium conophorum in male rats. Assays of biochemical reproductive parameters (total cholesterol, serum testosterone, FSH and LH) were carried out using Cypress and ELISA kits respectively. The chemical screening of the extract was conducted through tube reactions, the principle of which involves adding a reagent to a quantity of the extract, and subsequently observing the resulting reactions such as precipitation and color change. The results obtained showed that oral administration of the aqueous extract of Tetracarpidium conophorum (250 and 500 mg/kg) produced a significant increase (p Tetracarpidium conophorum kernels at the doses studied produced a very significant decrease in total cholesterol levels (p Tetracarpidium conophorum kernels could have hypocholesterolemic and steroidogenic potential. A study of the aqueous extract of Tetracarpidium conophorum on semen quality and oxidative stress parameters deserves to be conducted.The main aim of this study was to evaluate the steroidogenic effects and phytochemical profile of aqueous extract of Tetracarpidium conophorum in male rats. Assays of biochemical reproductive parameters (total cholesterol, serum testosterone, FSH and LH) were carried out using Cypress and ELISA kits respectively. The chemical screening of the extract was conducted through tube reactions, the principle of which involves adding a reagent to a quantity of the extract, and subsequently observing the resulting reactions such as precipitation and color change. The results obtained showed that oral administration of the aqueous extract of Tetracarpidium conophorum (250 and 500 mg/kg) produced a significant increase (p Tetracarpidium conophorum kernels at the doses studied produced a very significant decrease in total cholesterol levels (p Tetracarpidium conophorum kernels could have hypocholesterolemic and steroidogenic potential. A study of the aqueous extract of Tetracarpidium conophorum on semen quality and oxidative stress parameters deserves to be conducted.

关 键 词：Tetracarpidium conophorum Steroidogenic Chemical Screaming 

分 类 号：O17[理学—数学]