Analysis of the Cicatricial Acceleration Method (MAC®) in Skin Repair in Wistar Rattus norvegicus with Induced Chemical Burns  

作　　者：Marcus Vinicius de Mello Pinto Sandroval Francisco Torres Aline Ronis Sampaio Karin Yuri Fernandez Iturra Miriam Viviane Baron Patricia Froes Carlos Ruiz da Silva Daiane Paza Maria Elena Silva Alvarez Josefa Jeanette Ugalde Juliano Tibola Esteban Fortuny Marcus Vinicius de Mello Pinto;Sandroval Francisco Torres;Aline Ronis Sampaio;Karin Yuri Fernandez Iturra;Miriam Viviane Baron;Patricia Froes;Carlos Ruiz da Silva;Daiane Paza;Maria Elena Silva Alvarez;Josefa Jeanette Ugalde;Juliano Tibola;Esteban Fortuny(Celulare Institute, Petrpolis, Brazil;State University of Santa Catarina (UDESC), Florianopolis, Brazil;Bienus Clinic, Santiago, Chile;Pontifical Catholic University of Rio Grande do Sul (PUC/RS), Porto Alegre, Brazil;International Research Group (IRG), Natal, Brazil;Academic Training Center (CTA) College, So Paulo, Brazil;Fibrafisio Clinic, Brusque, Brazil;Fisiocare Clinic, Curic, Chile;Lua Clinic, Coyhaique, Chile;Finis Terrae University, Santiago, Chile)

机构地区：[1]Celulare Institute, Petrpolis, Brazil [2]State University of Santa Catarina (UDESC), Florianopolis, Brazil [3]Bienus Clinic, Santiago, Chile [4]Pontifical Catholic University of Rio Grande do Sul (PUC/RS), Porto Alegre, Brazil [5]International Research Group (IRG), Natal, Brazil [6]Academic Training Center (CTA) College, So Paulo, Brazil [7]Fibrafisio Clinic, Brusque, Brazil [8]Fisiocare Clinic, Curic, Chile [9]Lua Clinic, Coyhaique, Chile [10]Finis Terrae University, Santiago, Chile

出　　处：《Journal of Biosciences and Medicines》2024年第9期204-214,共11页生物科学与医学（英文）

摘　　要：Introduction: The cicatricial acceleration method (MAC®) promotes photobiological effects of an anti-inflammatory and healing nature. Its therapeutic radiation is emitted, producing photobiostimulant effects that result in rapid tissue repair and better tissue quality. The treatment of burns has always been a challenge, which involves both performing surgery and controlling and guiding scar regeneration, avoiding possible morbidities. Objective: To evaluate the effects of applying the MAC methodology with an AlGa (aluminum, gallium arsenide) laser on the time and quality of tissue repair in the skin of rats after induced chemical burns. Method: 22 adult male rats were subjected to a second-degree chemical burn on the back using 50% trichloroacetic acid. After the burns, the animals were randomly separated into 2 groups: control and experimental. The control group (G1) received placebo laser therapy and the laser group (G2) underwent laser irradiation with an energy density of 100 J/cm2. Histological analysis and macroscopic evaluation were carried out by means of the paper template method. Results: Group G1 showed (53%) of the necrosis area and group G2 showed (11%) necrosis area. Conclusion: The cicatricial acceleration method (MAC®) favored the repair of wounds caused by a 2nd-degree chemical burn, optimizing time and improving quality.Introduction: The cicatricial acceleration method (MAC®) promotes photobiological effects of an anti-inflammatory and healing nature. Its therapeutic radiation is emitted, producing photobiostimulant effects that result in rapid tissue repair and better tissue quality. The treatment of burns has always been a challenge, which involves both performing surgery and controlling and guiding scar regeneration, avoiding possible morbidities. Objective: To evaluate the effects of applying the MAC methodology with an AlGa (aluminum, gallium arsenide) laser on the time and quality of tissue repair in the skin of rats after induced chemical burns. Method: 22 adult male rats were subjected to a second-degree chemical burn on the back using 50% trichloroacetic acid. After the burns, the animals were randomly separated into 2 groups: control and experimental. The control group (G1) received placebo laser therapy and the laser group (G2) underwent laser irradiation with an energy density of 100 J/cm2. Histological analysis and macroscopic evaluation were carried out by means of the paper template method. Results: Group G1 showed (53%) of the necrosis area and group G2 showed (11%) necrosis area. Conclusion: The cicatricial acceleration method (MAC®) favored the repair of wounds caused by a 2nd-degree chemical burn, optimizing time and improving quality.

关 键 词：Chemical Burn HEALING SCARRING Cicatricial Acceleration Method (MAC®) Tissue Repair 

分 类 号：TN2[电子电信—物理电子学]