Distribution Characteristics of Drug Susceptibility Test Results of Tuberculosis and Non-Tuberculous Bacilli in Patients with Opportunistic Infections of AIDS  

作　　者：Qing Lin Lida Mo Xiaoye Su Lihua Qin Guosheng Su Qing Lin;Lida Mo;Xiaoye Su;Lihua Qin;Guosheng Su(Department of Infectious Diseases, People’s Hospital of Debao County, Debao, China;Department of Medical Laboratory Science, Nanning Fourth People’s Hospital, Nanning Infectious Disease Hospital Affiliated to Guangxi Medical University, Nanning, China;Guangxi AIDS Clinical Treatment Center, Nanning, China;Department of Nursing, Graduate College of Eternity, University of the Philippines, Quezon City, Philippines;Department of Critical Care Medicine, Fuzhou Second People’s Hospital, Fuzhou, China;The People’s Hospital of the Guangxi-ASEAN Economic and Technological Development Zone, Nanning, China;The First Department of Internal Medicine, Nanning Tenth People’s Hospital, Nanning, China;Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China;Department of Laboratory Medicine, The People’s Hospital of the Guangxi-ASEAN Economic and Technological Development Zone, Nanning Tenth People’s Hospital, Nanning, China)

机构地区：[1]Department of Infectious Diseases, People’s Hospital of Debao County, Debao, China [2]Department of Medical Laboratory Science, Nanning Fourth People’s Hospital, Nanning Infectious Disease Hospital Affiliated to Guangxi Medical University, Nanning, China [3]Guangxi AIDS Clinical Treatment Center, Nanning, China [4]Department of Nursing, Graduate College of Eternity, University of the Philippines, Quezon City, Philippines [5]Department of Critical Care Medicine, Fuzhou Second People’s Hospital, Fuzhou, China [6]The People’s Hospital of the Guangxi-ASEAN Economic and Technological Development Zone, Nanning, China [7]The First Department of Internal Medicine, Nanning Tenth People’s Hospital, Nanning, China [8]Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China [9]Department of Laboratory Medicine, The People’s Hospital of the Guangxi-ASEAN Economic and Technological Development Zone, Nanning Tenth People’s Hospital, Nanning, China

出　　处：《Journal of Tuberculosis Research》2021年第4期256-265,共10页结核病研究（英文）

摘　　要：<b><span style="font-family:Verdana;">Objective: </span></b><span style="font-family:;" "=""><span style="font-family:Verdana;">To understand the distribution of drug susceptibility test results of opportunistic infections of tuberculosis and non-tuberculous bacilli in AIDS patients. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">The AIDS patients who were hospitalized in our hospital from January 2016 to June 2019 were collected as the research objects, and patients with opportunistic tuberculosis and non-tuberculous bacilli from AIDS patients were screened for drug susceptibility tests, and the distribution characteristics of drug susceptibility were analyzed. </span><b><span style="font-family:Verdana;">Results: </span></b><span><span style="font-family:Verdana;">179 strains of tuberculosis and non-tuberculous mycobacteria were isolated from the specimens of AIDS patients, including 135 cases of tuberculosis mycobacteria and 44 cases of non-tuberculous mycobacteria. In the results of the drug susceptibility test, most strains of </span><i></i></span><i><i><span style="font-family:Verdana;">Mycobacterium tuberculosis</span></i><span></span></i><span style="font-family:Verdana;"> showed sensitivity to commonly used drugs, and a few strains showed resistance;most strains </span></span><span style="font-family:Verdana;">of non-tuberculous mycobacteria showed resistance, and a few strains showed</span><span style="font-family:Verdana;"> sensitivity. </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span><span style="font-family:Verdana;">AIDS opportunistic infection of </span><i></i></span><i><i><span style="font-family:Verdana;">Mycobacterium tuberculosis</span></i><span></span></i><span style="font-family:Verdana;"> and non-tuberculous mycobacteria have significant differences in drug sensitivity test results. Timely detection and analysis are of great significance to the diagnosis and treatment of the disease.</span><b><span style="font-family:Verdana;">Objective: </span></b><span style="font-family:;" "=""><span style="font-family:Verdana;">To understand the distribution of drug susceptibility test results of opportunistic infections of tuberculosis and non-tuberculous bacilli in AIDS patients. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">The AIDS patients who were hospitalized in our hospital from January 2016 to June 2019 were collected as the research objects, and patients with opportunistic tuberculosis and non-tuberculous bacilli from AIDS patients were screened for drug susceptibility tests, and the distribution characteristics of drug susceptibility were analyzed. </span><b><span style="font-family:Verdana;">Results: </span></b><span><span style="font-family:Verdana;">179 strains of tuberculosis and non-tuberculous mycobacteria were isolated from the specimens of AIDS patients, including 135 cases of tuberculosis mycobacteria and 44 cases of non-tuberculous mycobacteria. In the results of the drug susceptibility test, most strains of </span><i></i></span><i><i><span style="font-family:Verdana;">Mycobacterium tuberculosis</span></i><span></span></i><span style="font-family:Verdana;"> showed sensitivity to commonly used drugs, and a few strains showed resistance;most strains </span></span><span style="font-family:Verdana;">of non-tuberculous mycobacteria showed resistance, and a few strains showed</span><span style="font-family:Verdana;"> sensitivity. </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span><span style="font-family:Verdana;">AIDS opportunistic infection of </span><i></i></span><i><i><span style="font-family:Verdana;">Mycobacterium tuberculosis</span></i><span></span></i><span style="font-family:Verdana;"> and non-tuberculous mycobacteria have significant differences in drug sensitivity test results. Timely detection and analysis are of great significance to the diagnosis and treatment of the disease.</span>

关 键 词：AIDS Opportunistic Infections Mycobacterium Tuberculosis Complex Non-Tuberculous Mycobacteria 

分 类 号：R51[医药卫生—内科学]