Tuberculous Meningitis and COVID-19 Co-Infection: About a Case  

作　　者：Ayoub Maaroufi Abdellatif Diai Nouredine Jebbar Lotfi Bibiche Kaissi Jaber Nabil Jbili Hicham Kechna Jaouad Laoutid Ayoub Maaroufi;Abdellatif Diai;Nouredine Jebbar;Lotfi Bibiche;Kaissi Jaber;Nabil Jbili;Hicham Kechna;Jaouad Laoutid(CHU Hassan II, Fes, Morocco)

机构地区：[1]CHU Hassan II, Fes, Morocco

出　　处：《Open Journal of Clinical Diagnostics》2021年第2期52-58,共7页临床诊断学期刊（英文）

摘　　要：We report the case of an adult patient diagnosed with acute SARS-CoV-2-associated meningoencephalitis based on the detection of its RNA on a nasopharyngeal swab, cerebrospinal fluid analysis. The most destructive type of extrapulmonary tuberculosis is tuberculous meningitis, in which the consequences are severe, resulting in death or disability in almost half of all sufferers despite anti-tuberculosis chemotherapy. The aim of this study was to assess the clinical and paraclinical features and laboratory findings and outcome of a patient with tuberculous meningitis and COVID-19 coinfection. Infection of COVID-19 and lymphopenia promotes the development of the severe form of tuberculosis. On the other hand, TBM increased the risk of infection with coronavirus due to the weakened immune system in addition to other immunosuppressive factors (older age and comorbidities such as low socioeconomic status and malnutrition). The patient had a good recovery even if he required intensive neurorehabilitation for a month due to poor feeding and weakness. Treatment, both anti-mycobacterial and anti-inflammatory, early started, guaranteed good recovery.We report the case of an adult patient diagnosed with acute SARS-CoV-2-associated meningoencephalitis based on the detection of its RNA on a nasopharyngeal swab, cerebrospinal fluid analysis. The most destructive type of extrapulmonary tuberculosis is tuberculous meningitis, in which the consequences are severe, resulting in death or disability in almost half of all sufferers despite anti-tuberculosis chemotherapy. The aim of this study was to assess the clinical and paraclinical features and laboratory findings and outcome of a patient with tuberculous meningitis and COVID-19 coinfection. Infection of COVID-19 and lymphopenia promotes the development of the severe form of tuberculosis. On the other hand, TBM increased the risk of infection with coronavirus due to the weakened immune system in addition to other immunosuppressive factors (older age and comorbidities such as low socioeconomic status and malnutrition). The patient had a good recovery even if he required intensive neurorehabilitation for a month due to poor feeding and weakness. Treatment, both anti-mycobacterial and anti-inflammatory, early started, guaranteed good recovery.

关 键 词：Tuberculous Meningitis MENINGOENCEPHALITIS COVID-19 Critical Care 

分 类 号：R51[医药卫生—内科学]