Kaposi Sarcoma after Kidney Transplant: A Clinical Case Report  

作　　者：Meryem Benbella Zaineb Kaouiri Imane Saidi Naima Ouzedoun Tarik Bouattar Meryem Benbella;Zaineb Kaouiri;Imane Saidi;Naima Ouzedoun;Tarik Bouattar(Department of Nephrology-Dialysis-Renal Transplantation, Ibn Sina University Hospital in Rabat, Rabat, Morocco;Faculty of Medicine and Pharmacy in Rabat, Mohammed V University, Rabat, Morocco)

机构地区：[1]Department of Nephrology-Dialysis-Renal Transplantation, Ibn Sina University Hospital in Rabat, Rabat, Morocco [2]Faculty of Medicine and Pharmacy in Rabat, Mohammed V University, Rabat, Morocco

出　　处：《Open Journal of Nephrology》2024年第1期115-123,共9页肾脏病（英文）

摘　　要：Kaposi sarcoma is a neoplasm caused by human herpesvirus 8 (HHV8) that most commonly affects immunosuppressed patients. The skin is the most affected area, but other sites can be involved such as the lung, digestive tract and lymph nodes. The classical presentation involves a violaceous skin lesion that can be small or hidden, leading to a delay in diagnosis. We report a clinical case of a kidney transplant patient, who presented, 14 months after kidney transplant, with unilateral edema of the inferior member and cutaneous rash misdiagnosed and taken initially for erysipelas. The diagnosis of Kaposi’s sarcoma was retained, on a lymph node biopsy of an inguinal adenopathy. The evolution was marked by a local and general improvement after systemic chemotherapy, reducing Tacrolimus and discontinuation of Mycophenolate mofetil. Graft function remained stable during the follow-up.Kaposi sarcoma is a neoplasm caused by human herpesvirus 8 (HHV8) that most commonly affects immunosuppressed patients. The skin is the most affected area, but other sites can be involved such as the lung, digestive tract and lymph nodes. The classical presentation involves a violaceous skin lesion that can be small or hidden, leading to a delay in diagnosis. We report a clinical case of a kidney transplant patient, who presented, 14 months after kidney transplant, with unilateral edema of the inferior member and cutaneous rash misdiagnosed and taken initially for erysipelas. The diagnosis of Kaposi’s sarcoma was retained, on a lymph node biopsy of an inguinal adenopathy. The evolution was marked by a local and general improvement after systemic chemotherapy, reducing Tacrolimus and discontinuation of Mycophenolate mofetil. Graft function remained stable during the follow-up.

关 键 词：KAPOSI Kidney Transplant HHV8 IMMUNOSUPPRESSION 

分 类 号：R69[医药卫生—泌尿科学]