Refractive State and Macular Abnormalities at Oct in Albino at Chu Iota  

作　　者：Assiatou Simaga Mohamed Kolé Sidibé Ibrahima Conaré Nana Wangara Seydou Diallo Founè Keïta Adama Dembélé Nephthali Gnangourou Nouhoum Guirou Seydou Bakayoko Kalilou Ibrahim Gakou Hamidou Ibrahim Diepkilé Jeremy Dembélé Assiatou Simaga;Mohamed Kolé Sidibé;Ibrahima Conaré;Nana Wangara;Seydou Diallo;Founè Keïta;Adama Dembélé;Nephthali Gnangourou;Nouhoum Guirou;Seydou Bakayoko;Kalilou Ibrahim Gakou;Hamidou Ibrahim Diepkilé;Jeremy Dembélé(Institute of Ophthalmology and Tropical Africa (IOTA), Bamako, Mali)

机构地区：[1]Institute of Ophthalmology and Tropical Africa (IOTA), Bamako, Mali

出　　处：《Open Journal of Ophthalmology》2023年第3期267-272,共6页眼科学期刊（英文）

摘　　要：Introduction: A rare genetic disease, albinism is globally characterized by specific deficits of the visual system associated with a variable hypopigmentation phenotype depending on the disruption of melanin production [1]. It is linked to a hereditary defect in the biosynthesis of melanin. Disease results in a generalized decrease in the pigmentation of the appendages, skin and eyes [2]. The aim of this study is to determine the different refractive errors and the different macular anomalies during the OCT examination in oculocutaneous albinism at the CHU-IOTA. Patients and Method: We conducted a prospective study in patients over 10 years of age with oculocutaneous or ocular albinism who consulted at the CHU-IOTA between July 1, 2020, and September 30, 2021. Results: Over the period, 105 cases of oculocutaneous albinism were collected out of a total of 42,024 consultations, which corresponds to a frequency of 0.2%. The average age was 26.2 years, (11 years to 48 years). The sex ratio was 1.6. Astigmatism was the most found refractive error in 50.48% of cases, followed by myopia in 29.52% of cases and farsightedness in 20% of cases. The macular thickness between 251 - 350 was the most commonly found in both eyes, i.e. 47.25% on the right and 53.55% on the left. The bulging macula was the most frequent pathology on the OCT at the level of the two eyes, i.e. 41.42% on the right and 50.6% on the left. Conclusion: Following the visual impairments linked to albinism, early optical care and access to OCT are necessary. Thus the accompaniment of a subject with albinism and associations of albinism must be global and meet specific needs, in order to prevent or avoid ocular complications.Introduction: A rare genetic disease, albinism is globally characterized by specific deficits of the visual system associated with a variable hypopigmentation phenotype depending on the disruption of melanin production [1]. It is linked to a hereditary defect in the biosynthesis of melanin. Disease results in a generalized decrease in the pigmentation of the appendages, skin and eyes [2]. The aim of this study is to determine the different refractive errors and the different macular anomalies during the OCT examination in oculocutaneous albinism at the CHU-IOTA. Patients and Method: We conducted a prospective study in patients over 10 years of age with oculocutaneous or ocular albinism who consulted at the CHU-IOTA between July 1, 2020, and September 30, 2021. Results: Over the period, 105 cases of oculocutaneous albinism were collected out of a total of 42,024 consultations, which corresponds to a frequency of 0.2%. The average age was 26.2 years, (11 years to 48 years). The sex ratio was 1.6. Astigmatism was the most found refractive error in 50.48% of cases, followed by myopia in 29.52% of cases and farsightedness in 20% of cases. The macular thickness between 251 - 350 was the most commonly found in both eyes, i.e. 47.25% on the right and 53.55% on the left. The bulging macula was the most frequent pathology on the OCT at the level of the two eyes, i.e. 41.42% on the right and 50.6% on the left. Conclusion: Following the visual impairments linked to albinism, early optical care and access to OCT are necessary. Thus the accompaniment of a subject with albinism and associations of albinism must be global and meet specific needs, in order to prevent or avoid ocular complications.

关 键 词：Refractive Defects MACULA OCT Albinos CHU-IOTA 

分 类 号：TP3[自动化与计算机技术—计算机科学与技术]