Sydenham’s Chorea: Apropos of Three Observed Cases at the N’Djamena Mother and Child University Teaching Hospital (CHU-ME)-Chad  

作　　者：Hassan Adam Annour Mahamat Ali Bolti Ildjima Ousmane Kadallah Hamit Mahamat Alio Hassan Adam Annour;Mahamat Ali Bolti;Ildjima Ousmane Kadallah;Hamit Mahamat Alio(Teaching Hospital, Renaissance University Hospital, N’Djamena, Chad;Department of Pediatrie, Faculty of Human Health Sciences of the University of N’Djamena, N’Djamena, Chad;Internal Medicine Department, Faculty of Human Health Sciences of the University of N’Djamena, N’Djamena, Chad;Teaching Hospital, Mother and Child University, N’Djamena, Chad;Laboratory Department, Faculty of Human Health Sciences of the University of N’Djamena, N’Djamena, Chad)

机构地区：[1]Teaching Hospital, Renaissance University Hospital, N’Djamena, Chad [2]Department of Pediatrie, Faculty of Human Health Sciences of the University of N’Djamena, N’Djamena, Chad [3]Internal Medicine Department, Faculty of Human Health Sciences of the University of N’Djamena, N’Djamena, Chad [4]Teaching Hospital, Mother and Child University, N’Djamena, Chad [5]Laboratory Department, Faculty of Human Health Sciences of the University of N’Djamena, N’Djamena, Chad

出　　处：《Open Journal of Pediatrics》2023年第4期507-514,共8页儿科学期刊（英文）

摘　　要：Introduction: Post-streptococcal chorea is the most common form of acquired chorea in children. Objective: The objective of this study was to contribute to better management of this condition by giving the characteristics of the epidemiological, clinical, biological, etiological, therapeutic and evolutionary aspects. Methodology: This was a retrospective and descriptive study from January 2021 to December 2021 which took place in the pediatrics department of the Mother and Child University Teaching Hospital of N’Djamena (CHU-ME). All the children in whom we observed abnormal involuntary movements whose age was less than or equal to 15 years were concerned. Result: there were three female children. The average age was 7.5, of which the two are 7 years old and the third is 8 years old. Two had a history of angina. A notion of polyarthralgia and dental caries was found in the third. The diagnosis of post-streptococcal chorea was retained on the basis of clinical arguments: observation of abnormal movements of the limbs and the face, which are involuntary, sudden with an insidious and progressive onset, muscular hypotonia, and psychic disorder. Medical imaging, in particular echocardiography, which objectified two cases of associated rheumatic valvular disease. Remission was observed in all three children after two weeks of treatment with haloperidol, penicillin. Those with associated rheumatic valve disease also received corticosteroid therapy. Complete remission of chorea was observed in all three girls. Prophylaxis in two patients based on Penicillin V was instituted. Conclusion: Although less frequent, post-streptococcal chorea is still seen in our country and is still an important health problem that needs more real medical efforts.Introduction: Post-streptococcal chorea is the most common form of acquired chorea in children. Objective: The objective of this study was to contribute to better management of this condition by giving the characteristics of the epidemiological, clinical, biological, etiological, therapeutic and evolutionary aspects. Methodology: This was a retrospective and descriptive study from January 2021 to December 2021 which took place in the pediatrics department of the Mother and Child University Teaching Hospital of N’Djamena (CHU-ME). All the children in whom we observed abnormal involuntary movements whose age was less than or equal to 15 years were concerned. Result: there were three female children. The average age was 7.5, of which the two are 7 years old and the third is 8 years old. Two had a history of angina. A notion of polyarthralgia and dental caries was found in the third. The diagnosis of post-streptococcal chorea was retained on the basis of clinical arguments: observation of abnormal movements of the limbs and the face, which are involuntary, sudden with an insidious and progressive onset, muscular hypotonia, and psychic disorder. Medical imaging, in particular echocardiography, which objectified two cases of associated rheumatic valvular disease. Remission was observed in all three children after two weeks of treatment with haloperidol, penicillin. Those with associated rheumatic valve disease also received corticosteroid therapy. Complete remission of chorea was observed in all three girls. Prophylaxis in two patients based on Penicillin V was instituted. Conclusion: Although less frequent, post-streptococcal chorea is still seen in our country and is still an important health problem that needs more real medical efforts.

关 键 词：Sydenham Chorea AAR STREPTOCOCCUS CHU-ME CHAD 

分 类 号：H31[语言文字—英语]