Hematological Alterations in an Eastern Sudanese Chronic Kidney Disease Patient Population  

作　　者：Mohammed Omer Abaker Gibreel Sundus Kamal Ibrahim Wijdan Abdel Aziz Hassan Manar Yahia Mahjoub Leyla Mohammed Kheir Hamid Hibatellah Majzoub Abbas Nuha Fouzi Mohammed Mohammed Omer Abaker Gibreel;Sundus Kamal Ibrahim;Wijdan Abdel Aziz Hassan;Manar Yahia Mahjoub;Leyla Mohammed Kheir Hamid;Hibatellah Majzoub Abbas;Nuha Fouzi Mohammed(Secretariat of Academic Affairs, Port Sudan Ahlia University, Port Sudan, Sudan;Department of Hematology and Immunohematology, College of Graduate Studies, Port Sudan Ahlia University, Port Sudan, Sudan)

机构地区：[1]Secretariat of Academic Affairs, Port Sudan Ahlia University, Port Sudan, Sudan [2]Department of Hematology and Immunohematology, College of Graduate Studies, Port Sudan Ahlia University, Port Sudan, Sudan

出　　处：《Open Journal of Urology》2024年第6期359-367,共9页泌尿学期刊（英文）

摘　　要：Background: Chronic Kidney Disease (CKD), associated with a slow and progressive loss of kidney function over a period of several years, is an important clinical disaster with an increasing rate of morbidity and mortality especially in the least developed countries. Many hematological parameters are thought to alter dramatically during the course of the disease. These include white blood cells, red blood cells, and platelets. Methods: We tried, retrospectively, to evaluate the peripheral blood hematological alterations in a group of patients undergoing hemodialysis in an eastern Sudan dialysis center to add local medical information. Results: Anemia (Low hemoglobin and hematocrit) was detected in 94% of the patients’ group. Mean Erythrocyte count (3.32vs.4.76 (×109/L)), Hemoglobin concentration (9.4vs.13 (g/dl)), Hematocrit (28.7vs.38.7 (L/L)) and platelet count (296 vs. 238 (×109/L)) were significantly lower in the patients’ group than in the control group (P-values Conclusion: Five out of eight studied parameters (Red cell count, hemoglobin, hematocrit, mean cell hemoglobin concentration, and platelets count) have shown a significant alteration in CKD patients. As the complete blood count (CBC) test is the most utilized test in clinical laboratory practice, these alterations may be considered as early indicators for CKD. Furthermore, all patients with CKD must be routinely checked for these alterations.Background: Chronic Kidney Disease (CKD), associated with a slow and progressive loss of kidney function over a period of several years, is an important clinical disaster with an increasing rate of morbidity and mortality especially in the least developed countries. Many hematological parameters are thought to alter dramatically during the course of the disease. These include white blood cells, red blood cells, and platelets. Methods: We tried, retrospectively, to evaluate the peripheral blood hematological alterations in a group of patients undergoing hemodialysis in an eastern Sudan dialysis center to add local medical information. Results: Anemia (Low hemoglobin and hematocrit) was detected in 94% of the patients’ group. Mean Erythrocyte count (3.32vs.4.76 (×109/L)), Hemoglobin concentration (9.4vs.13 (g/dl)), Hematocrit (28.7vs.38.7 (L/L)) and platelet count (296 vs. 238 (×109/L)) were significantly lower in the patients’ group than in the control group (P-values Conclusion: Five out of eight studied parameters (Red cell count, hemoglobin, hematocrit, mean cell hemoglobin concentration, and platelets count) have shown a significant alteration in CKD patients. As the complete blood count (CBC) test is the most utilized test in clinical laboratory practice, these alterations may be considered as early indicators for CKD. Furthermore, all patients with CKD must be routinely checked for these alterations.

关 键 词：Chronic Kidney Disease Chronic Renal Failure Hematological Alterations CBC Eastern Sudan HEMODIALYSIS 

分 类 号：R69[医药卫生—泌尿科学]