Antimicrobial Resistance Patterns of Selected <i>Enterobacteriaceae</i>Isolated from Commercial Poultry Production Systems in Kiambu County, Kenya  

作　　者：James Gakunga Ndukui Joseph Kangangi Gikunju Gabriel Oluga Aboge John Mwaniki Samuel Kariuki James Mucunu Mbaria James Gakunga Ndukui;Joseph Kangangi Gikunju;Gabriel Oluga Aboge;John Mwaniki;Samuel Kariuki;James Mucunu Mbaria(Department of Public Health, Pharmacology and Toxicology, College of Agriculture and Veterinary Sciences, University of Nairobi, Kenya;Department of Nursing, Catholic University of Eastern Africa, Langata Campus, Nairobi, Kenya;Department of Medical Laboratory Sciences, College of Health Science, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya;Centre for Microbiology Research, Kenya Medical Research Centre, Nairobi, Kenya)

机构地区：[1]Department of Public Health, Pharmacology and Toxicology, College of Agriculture and Veterinary Sciences, University of Nairobi, Kenya [2]Department of Nursing, Catholic University of Eastern Africa, Langata Campus, Nairobi, Kenya [3]Department of Medical Laboratory Sciences, College of Health Science, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya [4]Centre for Microbiology Research, Kenya Medical Research Centre, Nairobi, Kenya

出　　处：《Pharmacology & Pharmacy》2021年第10期219-236,共18页药理与制药（英文）

摘　　要：<b><span style="font-family:Verdana;">Introduction:</span></b><span style="font-family:""><span style="font-family:Verdana;"> In the last two decades, the treatment of enteric infections has been complicated by the emergence of antimicrobial resistant strains. Occurrence of multidrug resistant Extended Spectrum Beta Lactamase (ESBL) producing </span><i><span style="font-family:Verdana;">Enterobactaeraceae</span></i><span style="font-family:Verdana;"> pose</span></span><span style="font-family:Verdana;">s</span><span style="font-family:""><span style="font-family:Verdana;"> the greatest risk to public health by raising morbidity and mortality by six folds in developing countries. The present study aims to determine the antibiotics resistance patterns of selected</span><i><span style="font-family:Verdana;"> Entero</span><span style="font-family:Verdana;">bacteriaceae</span></i><span style="font-family:Verdana;"> isolated from commercial poultry production systems i</span><span style="font-family:Verdana;">n Kiamb</span><span><span style="font-family:Verdana;">u County. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> A laboratory based cross-sectional study was co</span></span><span style="font-family:Verdana;">nducted in six purposively selected Sub-Counties of Kiambu County from October 2020, to February 2021. A total of 437 fecal samples were collected from each household. The antibiotic susceptibility testing using disk diffusion method w</span></span><span style="font-family:Verdana;">as</span><span style="font-family:""><span style="font-family:Verdana;"> used against </span><i><span style="font-family:Verdana;">E.</span></i></span><i><span style="font-family:""> </span></i><i><span style="font-family:Verdana;">coli</span></i><span style="font-family:""><span style="font-family:Verdana;">;</span><i><span style="font-family:Verdana;"> Salmonella spps.</span></i><span style="font-family:Verdana;">;</span><i><span style="font-family:Verdana;"> Shigella spps.</sp<b><span style="font-family:Verdana;">Introduction:</span></b><span style="font-family:""><span style="font-family:Verdana;"> In the last two decades, the treatment of enteric infections has been complicated by the emergence of antimicrobial resistant strains. Occurrence of multidrug resistant Extended Spectrum Beta Lactamase (ESBL) producing </span><i><span style="font-family:Verdana;">Enterobactaeraceae</span></i><span style="font-family:Verdana;"> pose</span></span><span style="font-family:Verdana;">s</span><span style="font-family:""><span style="font-family:Verdana;"> the greatest risk to public health by raising morbidity and mortality by six folds in developing countries. The present study aims to determine the antibiotics resistance patterns of selected</span><i><span style="font-family:Verdana;"> Entero</span><span style="font-family:Verdana;">bacteriaceae</span></i><span style="font-family:Verdana;"> isolated from commercial poultry production systems i</span><span style="font-family:Verdana;">n Kiamb</span><span><span style="font-family:Verdana;">u County. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> A laboratory based cross-sectional study was co</span></span><span style="font-family:Verdana;">nducted in six purposively selected Sub-Counties of Kiambu County from October 2020, to February 2021. A total of 437 fecal samples were collected from each household. The antibiotic susceptibility testing using disk diffusion method w</span></span><span style="font-family:Verdana;">as</span><span style="font-family:""><span style="font-family:Verdana;"> used against </span><i><span style="font-family:Verdana;">E.</span></i></span><i><span style="font-family:""> </span></i><i><span style="font-family:Verdana;">coli</span></i><span style="font-family:""><span style="font-family:Verdana;">;</span><i><span style="font-family:Verdana;"> Salmonella spps.</span></i><span style="font-family:Verdana;">;</span><i><span style="font-family:Verdana;"> Shigella spps.</sp

关 键 词：Antimicrobial Resistance Enterobacteraceae AST Commercial Poultry Production Multi-Drug Resistance 

分 类 号：O17[理学—数学]