Frequency and Antimicrobials Susceptibility Pattern of <i>Staphylococcus aureus</i>Associated with Wound Infections in Surgery Department, Wad Madani Teaching Hospital, Sudan  

作　　者：Sanaa M. Yousif Adam D. Abakar Bakri Y. M. Nour Salma O. Ibrahim Omer M. Abu Elhasan Mirgani A. Yousif Sitelbanat Yassin Hajer M. Hussien Mohamed Taj-Eldin Elhadi A. Ahmed Sanaa M. Yousif;Adam D. Abakar;Bakri Y. M. Nour;Salma O. Ibrahim;Omer M. Abu Elhasan;Mirgani A. Yousif;Sitelbanat Yassin;Hajer M. Hussien;Mohamed Taj-Eldin;Elhadi A. Ahmed(National Blood Bank, Ministry of Health, Khartoum, Sudan;Department of Medical Parasitology, Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan;Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan;Wad-Madani College of Medical Sciences and Technology, Wad Medani, Sudan;Faculty of Pharmacy, University of Gezira, Wad Medani, Sudan)

机构地区：[1]National Blood Bank, Ministry of Health, Khartoum, Sudan [2]Department of Medical Parasitology, Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan [3]Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan [4]Wad-Madani College of Medical Sciences and Technology, Wad Medani, Sudan [5]Faculty of Pharmacy, University of Gezira, Wad Medani, Sudan

出　　处：《Pharmacology & Pharmacy》2021年第12期334-343,共10页药理与制药（英文）

摘　　要：<b><span style="font-family:Verdana;">Background</span></b><span style="font-family:Verdana;">: Most</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">community and hospital acquired infections are due to </span><i><span style="font-family:Verdana;">Staphylococcus aureus,</span></i><span style="font-family:Verdana;"> these infections involve both local suppurative and systemic conditions. There is an increas</span></span><span style="font-family:Verdana;">e</span><span style="font-family:""><span style="font-family:Verdana;"> in the incidence rates of acquiring resistant strains of </span><i><span style="font-family:Verdana;">Staphylococcus aureus</span></i><span style="font-family:Verdana;"> in hospitals and community in Sudan. This study aims to detect frequency of </span><i><span style="font-family:Verdana;">Staphylococcus aureus </span></i><span style="font-family:Verdana;">isolated from surgical-sites infections (SSIs) and traumatic wounds, and to determine susceptibility to commonly used drugs. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">Prospective cross-sectional laboratory based study was followed, 250 patients admitted to Surgery Departments at Wad Madani Teaching Hospitals during 2019 and 2020 were recruited;with clinical manifestation of SSIs and or/traumatic wounds. Swab sample was taken from each participant and incubated aerobically on mannitol salt agar. Biochemical tests and 16rRNA gene used for </span><i><span style="font-family:Verdana;">Staphylococcus aureus</span></i><span style="font-family:Verdana;"> identification. Antimicrobial susceptibility was accomplished using Kirby Bauer disc diffusion technique. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Infection rate of wounds in males and females equal 71% (17/250) and 29% (73/250), while infection rate in the age group of 41 to 60 years was the highest with percentage of 49% (122<b><span style="font-family:Verdana;">Background</span></b><span style="font-family:Verdana;">: Most</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">community and hospital acquired infections are due to </span><i><span style="font-family:Verdana;">Staphylococcus aureus,</span></i><span style="font-family:Verdana;"> these infections involve both local suppurative and systemic conditions. There is an increas</span></span><span style="font-family:Verdana;">e</span><span style="font-family:""><span style="font-family:Verdana;"> in the incidence rates of acquiring resistant strains of </span><i><span style="font-family:Verdana;">Staphylococcus aureus</span></i><span style="font-family:Verdana;"> in hospitals and community in Sudan. This study aims to detect frequency of </span><i><span style="font-family:Verdana;">Staphylococcus aureus </span></i><span style="font-family:Verdana;">isolated from surgical-sites infections (SSIs) and traumatic wounds, and to determine susceptibility to commonly used drugs. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">Prospective cross-sectional laboratory based study was followed, 250 patients admitted to Surgery Departments at Wad Madani Teaching Hospitals during 2019 and 2020 were recruited;with clinical manifestation of SSIs and or/traumatic wounds. Swab sample was taken from each participant and incubated aerobically on mannitol salt agar. Biochemical tests and 16rRNA gene used for </span><i><span style="font-family:Verdana;">Staphylococcus aureus</span></i><span style="font-family:Verdana;"> identification. Antimicrobial susceptibility was accomplished using Kirby Bauer disc diffusion technique. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Infection rate of wounds in males and females equal 71% (17/250) and 29% (73/250), while infection rate in the age group of 41 to 60 years was the highest with percentage of 49% (122

关 键 词：Staphylococcus aureus Surgical-Sites WOUNDS Meropeneme SUDAN 

分 类 号：H31[语言文字—英语]