Beyond Body Shape: Exploring the Complex Link between ABSI and Arterial Stiffness in a Chinese Population  

作　　者：Xiaoqian Chen Junyun Yang Jinyu Yang Xiang Chen Lihua Li Xiaoqian Chen;Junyun Yang;Jinyu Yang;Xiang Chen;Lihua Li(Department of Gerontology, The First Affiliated Hospital of Dali University, Dali, China)

机构地区：[1]Department of Gerontology, The First Affiliated Hospital of Dali University, Dali, China

出　　处：《World Journal of Cardiovascular Diseases》2025年第2期69-86,共18页心血管病(英文)

摘　　要：Background: Obesity, particularly abdominal obesity, is a well-established risk factor for arterial stiffness (AS) and cardiovascular diseases. A Body Shape Index (ABSI) is a novel anthropometric measure designed to assess abdominal obesity, yet its association with AS remains inconclusive. This study aims to investigate the relationship between ABSI and AS indicators in a general population. Methods: This cross-sectional study included 721 participants from the general population of Dali, Yunnan Province, China. ABSI was calculated using a standardized formula. Univariate and multivariate linear regression analyses were performed to examine the associations between ABSI and AS indicators, including brachial-ankle pulse wave velocity (ba-PWV) and carotid-femoral pulse wave velocity (cf-PWV). Results: Higher ABSI tertiles were significantly associated with increased ba-PWV and cf-PWV compared to the lowest tertile (P ≤ 0.007). However, after adjusting for potential confounders, these associations became non-significant (P ≥ 0.058), suggesting that ABSI is not an independent predictor of AS. Conclusions: The initial association between ABSI and AS was attenuated after covariate adjustment, suggesting ABSI is not an independent AS marker. Further research is warranted to understand the complex interactions between ABSI and other cardiovascular risk factors and its potential role in AS risk assessment.Background: Obesity, particularly abdominal obesity, is a well-established risk factor for arterial stiffness (AS) and cardiovascular diseases. A Body Shape Index (ABSI) is a novel anthropometric measure designed to assess abdominal obesity, yet its association with AS remains inconclusive. This study aims to investigate the relationship between ABSI and AS indicators in a general population. Methods: This cross-sectional study included 721 participants from the general population of Dali, Yunnan Province, China. ABSI was calculated using a standardized formula. Univariate and multivariate linear regression analyses were performed to examine the associations between ABSI and AS indicators, including brachial-ankle pulse wave velocity (ba-PWV) and carotid-femoral pulse wave velocity (cf-PWV). Results: Higher ABSI tertiles were significantly associated with increased ba-PWV and cf-PWV compared to the lowest tertile (P ≤ 0.007). However, after adjusting for potential confounders, these associations became non-significant (P ≥ 0.058), suggesting that ABSI is not an independent predictor of AS. Conclusions: The initial association between ABSI and AS was attenuated after covariate adjustment, suggesting ABSI is not an independent AS marker. Further research is warranted to understand the complex interactions between ABSI and other cardiovascular risk factors and its potential role in AS risk assessment.

关 键 词：A Body Shape Index Anthropometric Index Pulse Wave Velocity Arterial Stiffness 

分 类 号：F42[经济管理—产业经济]