Antioxidant and Antiplasmodial Activities of Extracts from <i>Gardenia erubescens</i>Stapf et Hutch. and <i>Fadogia agrestis</i>Schweinf. ex Hiern. (Rubiaceae)  

作　　者：Mariama Kaba Combasséré-Chérif Hadidjatou Belem Benjamin Koama Assetou Sawadogo Sandrine Nadège Da Windmi Kagambéga Anne-Flora Drabo Roland Nâg-Tiéro Meda George Anicet Ouédraogo Mariama Kaba Combasséré-Chérif;Hadidjatou Belem;Benjamin Koama;Assetou Sawadogo;Sandrine Nadège Da;Windmi Kagambéga;Anne-Flora Drabo;Roland Nâg-Tiéro Meda;George Anicet Ouédraogo(Laboratory for Research and education in Animal Health and Biotechnologies, Nazi Boni University, Bobo-Dioulasso, Burkina Faso;Health Action Research Group, Ouagadougou, Burkina Faso;Laboratory of Pharmacology, Research Institute in Health Sciences, Bobo-Dioulasso, Burkina Faso)

机构地区：[1]Laboratory for Research and education in Animal Health and Biotechnologies, Nazi Boni University, Bobo-Dioulasso, Burkina Faso [2]Health Action Research Group, Ouagadougou, Burkina Faso [3]Laboratory of Pharmacology, Research Institute in Health Sciences, Bobo-Dioulasso, Burkina Faso

出　　处：《Open Journal of Applied Sciences》2020年第11期675-687,共13页应用科学（英文）

摘　　要：Two medicinal plants,<span> <i><span style="font-family:Verdana;">Gardenia</span></i> <i><span style="font-family:Verdana;">erubescens</span></i></span><span style="font-family:Verdana;"> and </span><i><span style="font-family:Verdana;">Fadogia</span></i><span style="font-family:Verdana;"> <i>agrestis</i></span><span style="font-family:Verdana;"> were selected</span><span style="font-family:;" "=""> <span style="font-family:Verdana;">to evaluate their biological activities. Their total phenolic and flavonoid contents</span> <span style="font-family:Verdana;">were assessed using folin-ciocalteu and aluminum chloride regents’ methods. The antioxidant activity was estimated using DPPH (1,1-diphényl-2-picrylhydrazyl),</span><span> </span><span style="font-family:Verdana;">ABTS (</span></span><span style="font-family:Verdana;">2,2’-azinobis-[3-ethylenzothiazoline-6-sulfonic acid]</span><span style="font-family:Verdana;">) and FRAP (ferric reducing antioxidant power). The antiplasmodial activity of the extracts</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> was determined </span><i><span style="font-family:Verdana;">in</span></i> <i><span style="font-family:Verdana;">vivo</span></i><span style="font-family:Verdana;"> on 42 NMRI mice. The results indicate that all the extracts from both two plants contain some polyphenols. The ethanolic extract of the leaves of </span><i><span style="font-family:Verdana;">Gardenia</span></i> <i><span style="font-family:Verdana;">erubescens</span></i><span style="font-family:Verdana;"> showed the best antioxidant activity by the method of DPPH. The aqueous extracts of the leaves of </span><i><span style="font-family:Verdana;">Gardenia</span></i> <i><span style="font-family:Verdana;">erubescens</span></i><span style="font-family:Verdana;"> and the whole plant of </span><i><span style="font-family:Verdana;">Fadogia</span></i> <i><span style="font-family:Verdana;">agrestis</span></i><span style="font-family:Verdana;"> have a reducing power similar to controlTwo medicinal plants,<span> <i><span style="font-family:Verdana;">Gardenia</span></i> <i><span style="font-family:Verdana;">erubescens</span></i></span><span style="font-family:Verdana;"> and </span><i><span style="font-family:Verdana;">Fadogia</span></i><span style="font-family:Verdana;"> <i>agrestis</i></span><span style="font-family:Verdana;"> were selected</span><span style="font-family:;" "=""> <span style="font-family:Verdana;">to evaluate their biological activities. Their total phenolic and flavonoid contents</span> <span style="font-family:Verdana;">were assessed using folin-ciocalteu and aluminum chloride regents’ methods. The antioxidant activity was estimated using DPPH (1,1-diphényl-2-picrylhydrazyl),</span><span> </span><span style="font-family:Verdana;">ABTS (</span></span><span style="font-family:Verdana;">2,2’-azinobis-[3-ethylenzothiazoline-6-sulfonic acid]</span><span style="font-family:Verdana;">) and FRAP (ferric reducing antioxidant power). The antiplasmodial activity of the extracts</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> was determined </span><i><span style="font-family:Verdana;">in</span></i> <i><span style="font-family:Verdana;">vivo</span></i><span style="font-family:Verdana;"> on 42 NMRI mice. The results indicate that all the extracts from both two plants contain some polyphenols. The ethanolic extract of the leaves of </span><i><span style="font-family:Verdana;">Gardenia</span></i> <i><span style="font-family:Verdana;">erubescens</span></i><span style="font-family:Verdana;"> showed the best antioxidant activity by the method of DPPH. The aqueous extracts of the leaves of </span><i><span style="font-family:Verdana;">Gardenia</span></i> <i><span style="font-family:Verdana;">erubescens</span></i><span style="font-family:Verdana;"> and the whole plant of </span><i><span style="font-family:Verdana;">Fadogia</span></i> <i><span style="font-family:Verdana;">agrestis</span></i><span style="font-family:Verdana;"> have a reducing power similar to control

关 键 词：Antiplasmodial Activity Antioxidant Activity Gardenia erubescens Fadogia agrestis 

分 类 号：R28[医药卫生—中药学]