Numerical Simulation of Flow Behavior in Basilar Bifurcation Aneurysms Based on 4-Dimensional Computed Tomography Angiography  

作　　者：Tomoaki Yamazaki Gaku Tanaka Ryuhei Yamaguchi Yodai Okazaki Hitomi Anzai Fujimaro Ishida Makoto Ohta Tomoaki Yamazaki;Gaku Tanaka;Ryuhei Yamaguchi;Yodai Okazaki;Hitomi Anzai;Fujimaro Ishida;Makoto Ohta(Graduate School of Engineering, Chiba University, Chiba, Japan;Institute of Fluid Science, Tohoku University, Sendai, Japan;School of Engineering, Tokyo Institute of Technology, Yokohama, Japan;Department of Neurosurgery, Mie Chuo Medical Centre, Tsu, Japan)

机构地区：[1]Graduate School of Engineering, Chiba University, Chiba, Japan [2]Institute of Fluid Science, Tohoku University, Sendai, Japan [3]School of Engineering, Tokyo Institute of Technology, Yokohama, Japan [4]Department of Neurosurgery, Mie Chuo Medical Centre, Tsu, Japan

出　　处：《World Journal of Mechanics》2021年第4期71-82,共12页力学国际期刊（英文）

摘　　要：Initiation, growth, and rupture of cerebral aneurysms are caused by hemodynamic factors. It is extensively accepted that the cerebral aneurysm wall is assumed to be rigid using computational fluid dynamics (CFD). Furthermore, fluid-structure interactions have been recently applied for simulation of an elastic cerebral aneurysm model. Herein, we examined cerebral aneurysm hemodynamics in a realistic moving boundary deformation model based on 4-dimensional computed tomographic angiography (4D-CTA) obtained by high time-resolution using numerical simulation. The aneurysm of the realistic moving deformation model based on 4D-CTA at each phase was constructed. The effect of small wall deformation on hemodynamic characteristics might be interested. So, four hemodynamic factors (wall shear stress, wall shear stress divergence, oscillatory shear index and residual residence time) were determined from the numerical simulation, and their behaviors were assessed in the basilar bifurcation aneurysm.Initiation, growth, and rupture of cerebral aneurysms are caused by hemodynamic factors. It is extensively accepted that the cerebral aneurysm wall is assumed to be rigid using computational fluid dynamics (CFD). Furthermore, fluid-structure interactions have been recently applied for simulation of an elastic cerebral aneurysm model. Herein, we examined cerebral aneurysm hemodynamics in a realistic moving boundary deformation model based on 4-dimensional computed tomographic angiography (4D-CTA) obtained by high time-resolution using numerical simulation. The aneurysm of the realistic moving deformation model based on 4D-CTA at each phase was constructed. The effect of small wall deformation on hemodynamic characteristics might be interested. So, four hemodynamic factors (wall shear stress, wall shear stress divergence, oscillatory shear index and residual residence time) were determined from the numerical simulation, and their behaviors were assessed in the basilar bifurcation aneurysm.

关 键 词：Basilar Bifurcation Aneurysm 4-Dimensional Computed Tomographic Angiography Moving Boundary Method 

分 类 号：O17[理学—数学]