Geographical Distribution of Arboviruses, Aedes aegypti and Aedes albopictus Vectors and Their Resistance to Insecticides in Africa: A Systematic Review  

作　　者：Shoukrat Ohuwa Toyin Bello Abdou Azaque Zoure Abdoul Karim Ouattara Dogfounianalo Somda Christelle Nadembega Dorcas Obiri-Yeboah Moussa Namountougou Abdoulaye Diabate Jacques Simpore Shoukrat Ohuwa Toyin Bello;Abdou Azaque Zoure;Abdoul Karim Ouattara;Dogfounianalo Somda;Christelle Nadembega;Dorcas Obiri-Yeboah;Moussa Namountougou;Abdoulaye Diabate;Jacques Simpore(Biomolecular Research Center Pietro Annigoni (CERBA), Ouagadougou, Burkina Faso;African Center of Excellence in Biotechnological Innovations for the Elimination of Vector-Borne Diseases (CEA/ITECH-MTV), Nazi BONI University, Bobo-Dioulasso, Burkina Faso;Health Science Research Institute (IRSS/CNRST), Ouagadougou, Burkina Faso;Molecular Biology and Molecular Genetics Laboratory (LABIOGENE) UFR/SVT, Joseph KI-ZERBO University, Ouagadougou, Burkina Faso;Manga University Centre, Norbert Zongo University, Koudougou, Burkina Faso;Department of Microbiology and Immunology, School of Medical Sciences, University of Cape Coast, Cape Coast, Ghana;Health Science Research Institute (IRSS/CNRST), Centre Muraz, Bobo-Dioulasso, Burkina Faso)

机构地区：[1]Biomolecular Research Center Pietro Annigoni (CERBA), Ouagadougou, Burkina Faso [2]African Center of Excellence in Biotechnological Innovations for the Elimination of Vector-Borne Diseases (CEA/ITECH-MTV), Nazi BONI University, Bobo-Dioulasso, Burkina Faso [3]Health Science Research Institute (IRSS/CNRST), Ouagadougou, Burkina Faso [4]Molecular Biology and Molecular Genetics Laboratory (LABIOGENE) UFR/SVT, Joseph KI-ZERBO University, Ouagadougou, Burkina Faso [5]Manga University Centre, Norbert Zongo University, Koudougou, Burkina Faso [6]Department of Microbiology and Immunology, School of Medical Sciences, University of Cape Coast, Cape Coast, Ghana [7]Health Science Research Institute (IRSS/CNRST), Centre Muraz, Bobo-Dioulasso, Burkina Faso

出　　处：《Advances in Entomology》2024年第4期249-274,共26页昆虫学（英文）

摘　　要：Background & Objectives: Epidemics of arboviruses such as Dengue, Chikungunya and Zika have been recorded in recent years indicating that Aedes aegypti and Aedes albopictus are both important and very active vectors in Africa. For vector control, insecticides are on the front line, unfortunately, reported resistance jeopardizes the effectiveness of this strategy. The objective of this review was to determine the geographical distribution and insecticide resistance mechanisms of Ae. aegypti and Ae. Albopictus in Africa. Methods: A systematic review of the literature in scientific databases (PubMed, Google Scholar, ScienceDirect, Hinari) allowed us to identify relevant articles on the geographical distribution of Aedes aegypti, Aedes albopictus and arboviral diseases. On the other hand, studies related to insecticides used in vector control against Aedes, associated resistances and their molecular and metabolic mechanisms. Results: A total of 94 studies met the inclusion criteria for this search. Aedes aegypti is reported in most of Africa, and Aedes albopictus in part. There is a re-emergence and outbreak of Arbovirus epidemics in West and Central Africa. The insecticides used were organochlorines, carbamates, organophosphates and pyrethroids. In Aedes, target site insensitivity and metabolic resistance would be the 2 main mechanisms of resistance to these insecticides. Interpretation & Conclusion: Resistance has been recorded in all four major classes of insecticides recommended by WHO for vector control and eradication. New vector control methods such as the use of plant extracts with larvicidal and adulticidal activities, advanced modern biotechnology techniques, and nanobiotechnology need to be developed.Background & Objectives: Epidemics of arboviruses such as Dengue, Chikungunya and Zika have been recorded in recent years indicating that Aedes aegypti and Aedes albopictus are both important and very active vectors in Africa. For vector control, insecticides are on the front line, unfortunately, reported resistance jeopardizes the effectiveness of this strategy. The objective of this review was to determine the geographical distribution and insecticide resistance mechanisms of Ae. aegypti and Ae. Albopictus in Africa. Methods: A systematic review of the literature in scientific databases (PubMed, Google Scholar, ScienceDirect, Hinari) allowed us to identify relevant articles on the geographical distribution of Aedes aegypti, Aedes albopictus and arboviral diseases. On the other hand, studies related to insecticides used in vector control against Aedes, associated resistances and their molecular and metabolic mechanisms. Results: A total of 94 studies met the inclusion criteria for this search. Aedes aegypti is reported in most of Africa, and Aedes albopictus in part. There is a re-emergence and outbreak of Arbovirus epidemics in West and Central Africa. The insecticides used were organochlorines, carbamates, organophosphates and pyrethroids. In Aedes, target site insensitivity and metabolic resistance would be the 2 main mechanisms of resistance to these insecticides. Interpretation & Conclusion: Resistance has been recorded in all four major classes of insecticides recommended by WHO for vector control and eradication. New vector control methods such as the use of plant extracts with larvicidal and adulticidal activities, advanced modern biotechnology techniques, and nanobiotechnology need to be developed.

关 键 词：AEDES ARBOVIRUS Insecticide Resistance Molecular and Metabolic Mechanisms AFRICA 

分 类 号：R38[医药卫生—医学寄生虫学]