Investigating Sexual Auto-Dissemination of Native Strain of Metarhizium pingshaense from Burkina Faso within Aedes aegypti Mosquitoes for Dengue Control Perspectives  

作　　者：Etienne Bilgo Domonbabele François de Sales Hien Souro Abel Millogo Edounou Jacques Gnambani Seni Ilboudo Abdoulaye Diabate Etienne Bilgo;Domonbabele François de Sales Hien;Souro Abel Millogo;Edounou Jacques Gnambani;Seni Ilboudo;Abdoulaye Diabate(Institut de Recherche en Sciences de la Sante (IRSS), Direction Rgionale de lOuest (DRO)/CNRST, Bobo-Dioulasso, Burkina Faso;Centre Muraz, Institut National de Sant Publique (INSP), Bobo Dioulasso, Burkina Faso;Sciences and Techniques Dpartment, Institut du Dvelopement Rural, Universit Nazi Boni, Bobo-Dioulasso, Burkina Faso)

机构地区：[1]Institut de Recherche en Sciences de la Sante (IRSS), Direction Rgionale de lOuest (DRO)/CNRST, Bobo-Dioulasso, Burkina Faso [2]Centre Muraz, Institut National de Sant Publique (INSP), Bobo Dioulasso, Burkina Faso [3]Sciences and Techniques Dpartment, Institut du Dvelopement Rural, Universit Nazi Boni, Bobo-Dioulasso, Burkina Faso

出　　处：《Advances in Entomology》2025年第1期61-67,共7页昆虫学(英文)

摘　　要：In Burkina Faso, recent dengue outbreaks were exacerbated by Aedes aegypti mosquitoes, which have developed resistance to conventional insecticides. This study investigates the potential of Metarhizium pingshaense Met_S26, a fungus from Burkina Faso, for controlling both endophilic and exophilic Aedes mosquitoes. Traditional interventions are less effective against mosquitoes resting outdoors, and the ability of the fungus to be sexually transmitted could enhance its efficacy. Aedes mosquitoes were reared and exposed to various concentrations of Metarhizium pingshaense to assess its virulence. The fungus showed significant efficacy, with lethal times (LT80) ranging from 8.67 to 11.83 days depending on the concentration. Furthermore, bioassays demonstrated effective sexual auto-dissemination, with substantial transmission of fungal spores between infected and uninfected mosquitoes, leading to lower survival rates in uninfected mates. This study highlights Metarhizium pingshaense Met_S26 as a promising tool for controlling both indoor and outdoor Aedes populations, complementing existing vector control strategies such as the Sterile Insect Technique (SIT) and Wolbachia-based approaches. Future research should explore integrating this fungus with other control methods for a comprehensive vector management strategy.In Burkina Faso, recent dengue outbreaks were exacerbated by Aedes aegypti mosquitoes, which have developed resistance to conventional insecticides. This study investigates the potential of Metarhizium pingshaense Met_S26, a fungus from Burkina Faso, for controlling both endophilic and exophilic Aedes mosquitoes. Traditional interventions are less effective against mosquitoes resting outdoors, and the ability of the fungus to be sexually transmitted could enhance its efficacy. Aedes mosquitoes were reared and exposed to various concentrations of Metarhizium pingshaense to assess its virulence. The fungus showed significant efficacy, with lethal times (LT80) ranging from 8.67 to 11.83 days depending on the concentration. Furthermore, bioassays demonstrated effective sexual auto-dissemination, with substantial transmission of fungal spores between infected and uninfected mosquitoes, leading to lower survival rates in uninfected mates. This study highlights Metarhizium pingshaense Met_S26 as a promising tool for controlling both indoor and outdoor Aedes populations, complementing existing vector control strategies such as the Sterile Insect Technique (SIT) and Wolbachia-based approaches. Future research should explore integrating this fungus with other control methods for a comprehensive vector management strategy.

关 键 词：Sexual Dissemination Metarhizium pingshaense Aedes aegypti DENGUE Burkina Faso 

分 类 号：R51[医药卫生—内科学]