Anomeric Proton and Carbon (H1-C1) NMR Chemical Shifts of Antigenic Mannans Obtained from Pathogenic Yeast <i>Candida tropicalis</i>  

作　　者：Takuya Kuraoka Takayoshi Yamada Yuki Takatsutsumi Yukiko Ogawa Hidemitsu Kobayashi Takuya Kuraoka;Takayoshi Yamada;Yuki Takatsutsumi;Yukiko Ogawa;Hidemitsu Kobayashi(Divisions of Microbiology, Department of Pharmaceutical Science, Nagasaki International University, Nagasaki, Japan;Divisions of Infection Control and Prevention, Department of Pharmaceutical Science, Nagasaki International University, Nagasaki, Japan)

机构地区：[1]Divisions of Microbiology, Department of Pharmaceutical Science, Nagasaki International University, Nagasaki, Japan [2]Divisions of Infection Control and Prevention, Department of Pharmaceutical Science, Nagasaki International University, Nagasaki, Japan

出　　处：《Advances in Microbiology》2021年第5期296-301,共6页微生物学（英文）

摘　　要：On two dimensional maps of ¹H-¹³C correlation spectroscopy (H-C COSY) analysis for the mannan of <i>Candida tropicalis</i>, nine cross peaks of anomeric proton and carbon were useful for the purpose of obtaining information on the chemical structure of this molecule. Namely, the mannans was comb-like structure constructed with the linear <i>α</i>-1,6-linked polymannnosyl backbone and several oligomannnosyl side chains composed of <i>α</i>-1,2-, <i>α</i>-1,3-, and <i>β</i>-1,2-linkages. Therefore, in the structural investigation of comb-like mannan, two-dimensional H-C COSY analysis is as useful as two-dimensional nuclear Hartmann-Hahn (HOHAHA) analysis.On two dimensional maps of ¹H-¹³C correlation spectroscopy (H-C COSY) analysis for the mannan of <i>Candida tropicalis</i>, nine cross peaks of anomeric proton and carbon were useful for the purpose of obtaining information on the chemical structure of this molecule. Namely, the mannans was comb-like structure constructed with the linear <i>α</i>-1,6-linked polymannnosyl backbone and several oligomannnosyl side chains composed of <i>α</i>-1,2-, <i>α</i>-1,3-, and <i>β</i>-1,2-linkages. Therefore, in the structural investigation of comb-like mannan, two-dimensional H-C COSY analysis is as useful as two-dimensional nuclear Hartmann-Hahn (HOHAHA) analysis.

关 键 词：Candida tropicalis Cell Wall Mannan Comb-Like Structure ¹H-¹³C Correlation Spectroscopy Anomeric Carbon Chemical Shift α-1 3-Linked Mannose 

分 类 号：O57[理学—粒子物理与原子核物理]