Antioxidant and Antimicrobial Capacities of Two Medicinal Plants Used against Urinary Infections in Burkina Faso  

作　　者：Sami Eric Kam Roland Nâg-Tiéro Meda Soufiane Domalick Sanou Windmi Kagambega Clarisse Ouedraogo Franck Téounviel Somda Isaac Saamou Boni Eliasse Zongo Daniel Kobo Gnada Azouman Da Benjamin Kouliga Koama Hermann Yempabou Ouoba Georges Anicet Ouedraogo Sami Eric Kam;Roland Nâg-Tiéro Meda;Soufiane Domalick Sanou;Windmi Kagambega;Clarisse Ouedraogo;Franck Téounviel Somda;Isaac Saamou Boni;Eliasse Zongo;Daniel Kobo Gnada;Azouman Da;Benjamin Kouliga Koama;Hermann Yempabou Ouoba;Georges Anicet Ouedraogo(Laboratoire de Recherche et d’Enseignement en Santé et Biotechnologies Animales, Université Nazi Boni, Bobo-Dioulasso, Burkina Faso;Laboratoire de Recherche en Bactériologie, INSP/Centre MURAZ, Bobo-Dioulasso, Burkina Faso;Laboratoire de Médicine et Pharmacopée Traditionnelle, Institut de Recherche en Sciences de la Santé, Direction Régionale de l’Ouest, Bobo-Dioulasso, Burkina Faso)

机构地区：[1]Laboratoire de Recherche et d’Enseignement en Santé et Biotechnologies Animales, Université Nazi Boni, Bobo-Dioulasso, Burkina Faso [2]Laboratoire de Recherche en Bactériologie, INSP/Centre MURAZ, Bobo-Dioulasso, Burkina Faso [3]Laboratoire de Médicine et Pharmacopée Traditionnelle, Institut de Recherche en Sciences de la Santé, Direction Régionale de l’Ouest, Bobo-Dioulasso, Burkina Faso

出　　处：《Advances in Microbiology》2022年第12期671-683,共13页微生物学（英文）

摘　　要：Objective: This study aimed to evaluate the antioxidant and antimicrobial capacities of extracts from Euphorbia hirta L. and Terminalia avicennioides GUILL & PERR. Methodology: The crude hydro-acetonic and aqueous extracts as well their fractionations were prepared. The total phenolic, flavonoids and tannins contents were assessed using the Folin-Ciocalteu, aluminum chloride and vanillin acid methods, respectively. The antioxidant and antibacterial activities were investigated using standard methods. Results: Euphorbia hirta showed significant contents of total phenolic and flavonoids in n-Butanol (145.14 ± 1.37 GAE/100mg extracts) and ethyl acetate (23.56 ± 0.68 mg QE/ 100mg extracts) fractions. Total tannins were high in hydro-acétonique extract (11.18 ± 0.31 mg TAE/100mg extracts) and aqueous fraction (11.12 ± 0.28 mg TAE/100mg extracts) of Terminalia avicennioides stem barks. Extracts and fractions of both plants demonstrated a strongly antioxidant capacity through the free radicals scavenging and the ferric ions reducing. Concerning antimicrobial screening the extracts of Terminalia avicennioides were effective against 16 causative pathogens of urinary tract infections. Bactericidal effect against Staphylococcus aureus ATCC 29213, Staphylococcus aureus and 2 methicillin-resistant Staphylococcus haemolyticus strains was found with aqueous fraction of Terminalia avicennioides leaves. This fraction also highlighted a synergetic effect with some antibiotics used against these bacterial strains. Conclusion: Terminalia avicennioides leaves could be recommended as an herbal drug formulation for the urinary infections management.Objective: This study aimed to evaluate the antioxidant and antimicrobial capacities of extracts from Euphorbia hirta L. and Terminalia avicennioides GUILL & PERR. Methodology: The crude hydro-acetonic and aqueous extracts as well their fractionations were prepared. The total phenolic, flavonoids and tannins contents were assessed using the Folin-Ciocalteu, aluminum chloride and vanillin acid methods, respectively. The antioxidant and antibacterial activities were investigated using standard methods. Results: Euphorbia hirta showed significant contents of total phenolic and flavonoids in n-Butanol (145.14 ± 1.37 GAE/100mg extracts) and ethyl acetate (23.56 ± 0.68 mg QE/ 100mg extracts) fractions. Total tannins were high in hydro-acétonique extract (11.18 ± 0.31 mg TAE/100mg extracts) and aqueous fraction (11.12 ± 0.28 mg TAE/100mg extracts) of Terminalia avicennioides stem barks. Extracts and fractions of both plants demonstrated a strongly antioxidant capacity through the free radicals scavenging and the ferric ions reducing. Concerning antimicrobial screening the extracts of Terminalia avicennioides were effective against 16 causative pathogens of urinary tract infections. Bactericidal effect against Staphylococcus aureus ATCC 29213, Staphylococcus aureus and 2 methicillin-resistant Staphylococcus haemolyticus strains was found with aqueous fraction of Terminalia avicennioides leaves. This fraction also highlighted a synergetic effect with some antibiotics used against these bacterial strains. Conclusion: Terminalia avicennioides leaves could be recommended as an herbal drug formulation for the urinary infections management.

关 键 词：ANTIMICROBIAL ANTIOXIDANT Euphorbia hirta L. Terminalia avicennioides GUILL & PERR Urinary Infections 

分 类 号：R28[医药卫生—中药学]