Antibacteria Activity of Peganum harmala and Haloxylon salicornicum Leaves Extracts  

作　　者：Naif M. Alhawiti Agnes K. Nthenge Waeel H. Alramadhan William Boadi Abdulrahman F. Alqahtani Elber-Lewis Myles Naif M. Alhawiti;Agnes K. Nthenge;Waeel H. Alramadhan;William Boadi;Abdulrahman F. Alqahtani;Elber-Lewis Myles(CAHFS, University of California, Davis, USA;Department of Agricultural and Environmental Sciences, College of Agriculture, Tennessee State University, Nashville, USA;Department of Biological Science, Tennessee State University, Nashville, USA;Department of Chemistry, Tennessee State University, Nashville, USA;Saudi Food and Drug Authority, Riyadh, Saudi Arabia)

机构地区：[1]CAHFS, University of California, Davis, USA [2]Department of Agricultural and Environmental Sciences, College of Agriculture, Tennessee State University, Nashville, USA [3]Department of Biological Science, Tennessee State University, Nashville, USA [4]Department of Chemistry, Tennessee State University, Nashville, USA [5]Saudi Food and Drug Authority, Riyadh, Saudi Arabia

出　　处：《Advances in Microbiology》2024年第2期122-136,共15页微生物学（英文）

摘　　要：The use of antibiotics in humans and animals has been marked as a significant step in health due to their effectiveness in controlling and treating bacterial infections. The misuse and overuse of antibiotics have been identified as risk factors for bacterial resistance since microorganisms adapt and develop mechanisms to defend against antibiotics. According to the Centers for Disease Protection and Control (CDC), around 23,000 individuals die every year in the United States due to antibiotic resistance complications. As a result, a demand for alternative treatments has been a goal for scientists as the microbes adapt to selective pressure. The aim of this study is to test the antibacterial activity of leaf extracts of Peganum harmala and Haloxylon salicornicum on both Gram-positive and Gram-negative bacteria on various mediums. The results of the study showed that both P. harmala and H. salicornicum inhibited the bacterial growth in two different media. The results were also compared with different common antibiotics used in both human’s and animal’s fields and showed a promising outcome as alternative antibiotics.The use of antibiotics in humans and animals has been marked as a significant step in health due to their effectiveness in controlling and treating bacterial infections. The misuse and overuse of antibiotics have been identified as risk factors for bacterial resistance since microorganisms adapt and develop mechanisms to defend against antibiotics. According to the Centers for Disease Protection and Control (CDC), around 23,000 individuals die every year in the United States due to antibiotic resistance complications. As a result, a demand for alternative treatments has been a goal for scientists as the microbes adapt to selective pressure. The aim of this study is to test the antibacterial activity of leaf extracts of Peganum harmala and Haloxylon salicornicum on both Gram-positive and Gram-negative bacteria on various mediums. The results of the study showed that both P. harmala and H. salicornicum inhibited the bacterial growth in two different media. The results were also compared with different common antibiotics used in both human’s and animal’s fields and showed a promising outcome as alternative antibiotics.

关 键 词：Peganum harmala Haloxylon salicornicum Antibiotics Resistance Medicinal Plants GRAM-POSITIVE GRAM-NEGATIVE 

分 类 号：R28[医药卫生—中药学]