Joint Effects of Mexidol and Nitroglycerine on Nitric Oxide Formation in Animal Liver Tissues  

作　　者：Taasilkan Zhumabaeva Zoya Kuropteva Zhoomart Moldaliev Nazgul Zhumabaeva Amanai Kadyrbaeva Nurbek Bopoev Zhypargul Abdullaeva Taasilkan Zhumabaeva;Zoya Kuropteva;Zhoomart Moldaliev;Nazgul Zhumabaeva;Amanai Kadyrbaeva;Nurbek Bopoev;Zhypargul Abdullaeva(Department of Natural Sciences, Osh State University, Osh, Kyrgyzstan;Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russia;Department of Medicine, Kyrgyz-Turkish University Manas, Bishkek, Kyrgyzstan;Department of Hospital Therapy, Zhalal-Abad State University, Zhalal-Abad, Kyrgyzstan;International Hope School Bangladesh of Gulshan Branch, Dhaka, Bangladesh;Science and Research Department, Osh State University, Osh, Kyrgyzstan)

机构地区：[1]Department of Natural Sciences, Osh State University, Osh, Kyrgyzstan [2]Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russia [3]Department of Medicine, Kyrgyz-Turkish University Manas, Bishkek, Kyrgyzstan [4]Department of Hospital Therapy, Zhalal-Abad State University, Zhalal-Abad, Kyrgyzstan [5]International Hope School Bangladesh of Gulshan Branch, Dhaka, Bangladesh [6]Science and Research Department, Osh State University, Osh, Kyrgyzstan

出　　处：《American Journal of Molecular Biology》2021年第3期73-82,共10页美国分子生物学期刊（英文）

摘　　要：This work is investigating Mexidol (2-ethyl-6-methyl-3-hydroxy pyridine succinate) effect on the formation of nitric oxide (NO) in animal liver tissues, which is a regulator of many physiological processes and plays an important role in the vascular relaxation, neurotransmission and immune system functioning. Analyses performed by EPR spectroscopy revealed Hem-NO complex signals from paramagnetic centers in arbitrary units;produced nitrogen oxide amount in liver tissues was determined by method of double integration signals from nitrosyl complexes.This work is investigating Mexidol (2-ethyl-6-methyl-3-hydroxy pyridine succinate) effect on the formation of nitric oxide (NO) in animal liver tissues, which is a regulator of many physiological processes and plays an important role in the vascular relaxation, neurotransmission and immune system functioning. Analyses performed by EPR spectroscopy revealed Hem-NO complex signals from paramagnetic centers in arbitrary units;produced nitrogen oxide amount in liver tissues was determined by method of double integration signals from nitrosyl complexes.

关 键 词：NITROGLYCERINE Liver Tissue Nitric Oxide MEXIDOL Joint Effect EPR Spectra 

分 类 号：O62[理学—有机化学]