Evaluation of the Pharmacological Potential of Strychnos camptoneura Trunk Bark Hydroethanol Extract on Reproductive Functions in Male Guinea Pigs (Cavia porcellus) Exposed to Cypermethrin  

作　　者：Akassa Herman Moukouma Constantin Diakouka Diambalou Rancia Colombe Njilo Tchatchouang Didier Gestil Mouzita Judicaël Ferry Mpika M’boko Etou Ossibi Arnaud Wilfrid Abena Ange Antoine Akassa Herman;Moukouma Constantin;Diakouka Diambalou Rancia Colombe;Njilo Tchatchouang Didier Gestil;Mouzita Judicaël Ferry;Mpika M’boko;Etou Ossibi Arnaud Wilfrid;Abena Ange Antoine(Biochemical and Pharmacological Laboratory, Health Sciences Faculty, Marien Ngouabi University, Brazzaville, Congo;Biotechnology and Animal Physiology Laboratory, Ecole Nationale Suprieure dAgronomie et de Foresterie (ENSAF), Marien Ngouabi University, Brazzaville, Congo;National Institute of Research in Health Sciences (IRSSA), Brazzaville, Congo;National Laboratory of Public Health, Brazzaville, Congo;Chemistry Unit of the Plant and Life, Faculty of the Sciences and Techniques, Marien Ngouabi University, Brazzaville, Congo;Denis Sassou Nguesso University, Kintl, Republic of Congo)

机构地区：[1]Biochemical and Pharmacological Laboratory, Health Sciences Faculty, Marien Ngouabi University, Brazzaville, Congo [2]Biotechnology and Animal Physiology Laboratory, Ecole Nationale Suprieure dAgronomie et de Foresterie (ENSAF), Marien Ngouabi University, Brazzaville, Congo [3]National Institute of Research in Health Sciences (IRSSA), Brazzaville, Congo [4]National Laboratory of Public Health, Brazzaville, Congo [5]Chemistry Unit of the Plant and Life, Faculty of the Sciences and Techniques, Marien Ngouabi University, Brazzaville, Congo [6]Denis Sassou Nguesso University, Kintl, Republic of Congo

出　　处：《American Journal of Plant Sciences》2024年第10期884-898,共15页美国植物学期刊（英文）

摘　　要：The main objective of this study was to evaluate the pharmacological potential of the hydroethanol extract of Strychnos camptoneura trunk bark on reproductive functions in male guinea pigs exposed to cypermethrin. The results showed that administration of the hydroethanolic extract (100 and 250 mg/kg) of Strychnos camptoneura trunk bark after exposure of the animals to cypermethrin induced a highly significant (p Strychnos camptoneura trunk bark produced a highly significant (p Strychnos camptoneura trunk bark may have protective effects against cypermethrin-induced male infertility due to its androgenic, spermatogenic and antiradical properties.The main objective of this study was to evaluate the pharmacological potential of the hydroethanol extract of Strychnos camptoneura trunk bark on reproductive functions in male guinea pigs exposed to cypermethrin. The results showed that administration of the hydroethanolic extract (100 and 250 mg/kg) of Strychnos camptoneura trunk bark after exposure of the animals to cypermethrin induced a highly significant (p Strychnos camptoneura trunk bark produced a highly significant (p Strychnos camptoneura trunk bark may have protective effects against cypermethrin-induced male infertility due to its androgenic, spermatogenic and antiradical properties.

关 键 词：Strychnos Camptoneura Guinea Pig Males CYPERMETHRIN Reproductive Function 

分 类 号：S82[农业科学—畜牧学]