Green Tea(Camellia sinensis):Hypocholesterolemic Effects in Humans and Anti-Inflammatory Effects in Animals  

作　　者：Márcia Reto Cristina Almeida Joao Rocha Bruno Sepodes Maria-Eduardo Figueira 

机构地区：[1]Research Institute for Medicines(iMed.ULisboa),Faculty of Pharmacy,University of Lisbon,Lisbon,Portugal

出　　处：《Food and Nutrition Sciences》2014年第22期2185-2194,共10页食品与营养科学（英文）

摘　　要：In its essence, tea is an infusion of Camellia sinensis leaves and it is the most widely consumed beverage in the world, aside water. Animal and epidemiological studies have associated green tea consumption with several health benefits, which include hypocholesterolemic effect and anti-in-flammatory activity. In this study catechins levels of green tea and its effect on the lipid profile of humans were evaluated as well as the protective effects against H2O2-mediated damage in human fibroblasts and anti-inflammatory activity of (–)-epigallocatechingallate (EGCG). The daily consumption of 1200 mL of green tea for 30 days by 15 human volunteers promoted the decrease of cholesterol and LDL levels after 15 days, but this effect was not persistent after 30 days. No changes were observed in lipid profile after the consumption of green tea capsules. EGCG, a major green tea catechin, demonstrated an anti-inflammatory action in rats and an antioxidant effect in cultured human fibroblasts.In its essence, tea is an infusion of Camellia sinensis leaves and it is the most widely consumed beverage in the world, aside water. Animal and epidemiological studies have associated green tea consumption with several health benefits, which include hypocholesterolemic effect and anti-in-flammatory activity. In this study catechins levels of green tea and its effect on the lipid profile of humans were evaluated as well as the protective effects against H2O2-mediated damage in human fibroblasts and anti-inflammatory activity of (–)-epigallocatechingallate (EGCG). The daily consumption of 1200 mL of green tea for 30 days by 15 human volunteers promoted the decrease of cholesterol and LDL levels after 15 days, but this effect was not persistent after 30 days. No changes were observed in lipid profile after the consumption of green tea capsules. EGCG, a major green tea catechin, demonstrated an anti-inflammatory action in rats and an antioxidant effect in cultured human fibroblasts.

关 键 词：Green Tea INFUSIONS Hypocholesterolemic Effect Anti-Inflammatory Activity Antioxidant Activity 

分 类 号：R28[医药卫生—中药学]