Chemical Composition and Biological Significance of Thymol as Antiparasitic  

作　　者：Wafaa M. Hikal Kirill G. Tkachenko Hussein A. H. Said-Al Ahl Hoda Sany Ali S. Sabra Rowida S. Baeshen Amra Bratovcic Wafaa M. Hikal;Kirill G. Tkachenko;Hussein A. H. Said-Al Ahl;Hoda Sany;Ali S. Sabra;Rowida S. Baeshen;Amra Bratovcic(Department of Biology, Faculty of Science, University of Tabuk, Tabuk, KSA;Water Pollution Research Department, Environmental Research Division, National Research Centre, Giza, Egypt;V. L. Komarov Botanical Institute of the Russian Academy of Sciences, Saint Petersburg, Russia;Medicinal and Aromatic Plants Research Department, National Research Centre, Giza, Egypt;Department of Botany (Plant Physiology Section), Faculty of Agriculture, Cairo University, Giza, Egypt;Department of Physical Chemistry and Electrochemistry, Faculty of Technology, University of Tuzla, Tuzla, Bosnia and Herzegovina)

机构地区：[1]Department of Biology, Faculty of Science, University of Tabuk, Tabuk, KSA [2]Water Pollution Research Department, Environmental Research Division, National Research Centre, Giza, Egypt [3]V. L. Komarov Botanical Institute of the Russian Academy of Sciences, Saint Petersburg, Russia [4]Medicinal and Aromatic Plants Research Department, National Research Centre, Giza, Egypt [5]Department of Botany (Plant Physiology Section), Faculty of Agriculture, Cairo University, Giza, Egypt [6]Department of Physical Chemistry and Electrochemistry, Faculty of Technology, University of Tuzla, Tuzla, Bosnia and Herzegovina

出　　处：《Open Journal of Ecology》2021年第3期240-266,共27页生态学期刊（英文）

摘　　要：Thymol is one of the most important phytochemical components because of its pharmacological and bioactive potential effects. This review focuses particularly on thymol as an alternative natural antiparasitic with potential use in the pharmaceutical industry. This is in line with the preferences of the natural products for treatment being safer and without side effects. The biosynthesis pathways of thymol and carvacrol have been discussed, and mechanism of action of thymol on parasites. Studies on thymol confirmed the activity of thymol as anti-parasite against anthelmintic, <em>Trypanosoma</em> ssp., <em>Toxoplasma gondii</em>, <em>Leishmania</em> spp., <em>Plasmodium falciparum</em>, <em>Giardia duodenalis</em>, <em>Eimeria</em> ssp., <em>Cryptosporidium baileyi </em>and<em> Cryptosporidium galli</em>.Thymol is one of the most important phytochemical components because of its pharmacological and bioactive potential effects. This review focuses particularly on thymol as an alternative natural antiparasitic with potential use in the pharmaceutical industry. This is in line with the preferences of the natural products for treatment being safer and without side effects. The biosynthesis pathways of thymol and carvacrol have been discussed, and mechanism of action of thymol on parasites. Studies on thymol confirmed the activity of thymol as anti-parasite against anthelmintic, <em>Trypanosoma</em> ssp., <em>Toxoplasma gondii</em>, <em>Leishmania</em> spp., <em>Plasmodium falciparum</em>, <em>Giardia duodenalis</em>, <em>Eimeria</em> ssp., <em>Cryptosporidium baileyi </em>and<em> Cryptosporidium galli</em>.

关 键 词：THYMOL Chemical Composition Biological Activity ANTIPARASITIC 

分 类 号：R53[医药卫生—内科学]