Canine Leptospirosis Serology in Southern Mexico City  

作　　者：Ignacio Martínez-Barbabosa Edubiel Arturo Alpizar-Sosa Dolores Guadalupe Gavaldón-Rosas Luís Pedro Moles-Cervantes Marcia Gutiérrez Cárdenas Rafael García-González Michael Shea Ana María Fernández-Presas Ignacio Martínez-Barbabosa;Edubiel Arturo Alpizar-Sosa;Dolores Guadalupe Gavaldón-Rosas;Luís Pedro Moles-Cervantes;Marcia Gutiérrez Cárdenas;Rafael García-González;Michael Shea;Ana María Fernández-Presas(Health Attention Department, Human Parasitology Laboratory, Universidad Autónoma Metropolitana-Xochimilco, México DF, México;Animal and Agriculture Production Department, Universidad Autónoma Metropolitana-Xochimilco, México DF, México;Microbiology and Parasitology Department, School of Medicine, Universidad Autónoma de México, México DF, México;Education and Communication Department, Universidad Autónoma Metropolitana-Xochimilco, México DF, México)

机构地区：[1]Health Attention Department, Human Parasitology Laboratory, Universidad Autónoma Metropolitana-Xochimilco, México DF, México [2]Animal and Agriculture Production Department, Universidad Autónoma Metropolitana-Xochimilco, México DF, México [3]Microbiology and Parasitology Department, School of Medicine, Universidad Autónoma de México, México DF, México [4]Education and Communication Department, Universidad Autónoma Metropolitana-Xochimilco, México DF, México

出　　处：《Open Journal of Medical Microbiology》2016年第4期171-180,共10页医学微生物学（英文）

摘　　要：Background: Leptospirosis is an important zooanthroponotic disease spread worldwide which infection is recognized as a re-emergent disease. Leptospirosis is a systemic disease of humans and domestic animals, mainly dogs, cattle and swine, characterized by fever, renal and hepatic insufficiency, pulmonary manifestations and reproductive failure. Objective: To study the seroprevalence of anti-Leptospira antibodies in an urban canine population. Materials and Methods: The study was performed in March 2014 in stray dogs that had been captured in the districts of Coyoacan, Iztapalapa, Iztacalco and Benito Juarez in Mexico City;117 dogs were analyzed, from each of which 5 ml of blood were obtained. Serology was performed using a MAT test (Microscopic Agglutination Test), finding that the antigens corresponded to 13 serotypes of Leptospirainterrogans. Three age groups were formed: Group 1) younger than a year (n = 28), Group 2) 1 to 6 years (n = 75), and Group 3) older than 6 years (n = 14). Results: Of the analyzed sera, 28.2% were seropositive to one or more Leptospira serotypes, 74% of the positive seracoagglutinated with two or more serotypes. The most frequent serotypes were: Canicola, Icterohaemorrhagiae and Portland-vere. Serotypes Canicola, Pyrogenes, and Bratislava resulted statistically significant (p 0.001). The presence of anti-Leptospira antibodies in the blood of animals of 1 to 6 years resulted with a p 0.001. The sera from Iztapalapa reacted to nine serotypes. Conclusion: The 28.2% of seropositivity indicates Leptospira transmission in the canine population that was studied could exhibit a potential public health risk.Background: Leptospirosis is an important zooanthroponotic disease spread worldwide which infection is recognized as a re-emergent disease. Leptospirosis is a systemic disease of humans and domestic animals, mainly dogs, cattle and swine, characterized by fever, renal and hepatic insufficiency, pulmonary manifestations and reproductive failure. Objective: To study the seroprevalence of anti-Leptospira antibodies in an urban canine population. Materials and Methods: The study was performed in March 2014 in stray dogs that had been captured in the districts of Coyoacan, Iztapalapa, Iztacalco and Benito Juarez in Mexico City;117 dogs were analyzed, from each of which 5 ml of blood were obtained. Serology was performed using a MAT test (Microscopic Agglutination Test), finding that the antigens corresponded to 13 serotypes of Leptospirainterrogans. Three age groups were formed: Group 1) younger than a year (n = 28), Group 2) 1 to 6 years (n = 75), and Group 3) older than 6 years (n = 14). Results: Of the analyzed sera, 28.2% were seropositive to one or more Leptospira serotypes, 74% of the positive seracoagglutinated with two or more serotypes. The most frequent serotypes were: Canicola, Icterohaemorrhagiae and Portland-vere. Serotypes Canicola, Pyrogenes, and Bratislava resulted statistically significant (p 0.001). The presence of anti-Leptospira antibodies in the blood of animals of 1 to 6 years resulted with a p 0.001. The sera from Iztapalapa reacted to nine serotypes. Conclusion: The 28.2% of seropositivity indicates Leptospira transmission in the canine population that was studied could exhibit a potential public health risk.

关 键 词：LEPTOSPIRA LEPTOSPIROSIS Canicola Icterohaemorrhagiae DOGS 

分 类 号：F42[经济管理—产业经济]