<i>Bacillus cereus</i>Group Exhibits More Resistant to Chlorhexidine Rather Than <i>Bacillus subtilis</i>Group  

作　　者：Akira Okamoto Saki Otsuji Miho Kamako Ikumi Inoue Kokoro Tasaka Juntaro Kato Akira Okamoto;Saki Otsuji;Miho Kamako;Ikumi Inoue;Kokoro Tasaka;Juntaro Kato(School Health Sciences, Aichi University of Education, Kariya, Japan;Department of Biology, Aichi University of Education, Kariya, Japan)

机构地区：[1]School Health Sciences, Aichi University of Education, Kariya, Japan [2]Department of Biology, Aichi University of Education, Kariya, Japan

出　　处：《Open Journal of Medical Microbiology》2020年第3期139-152,共14页医学微生物学（英文）

摘　　要：<span "="" style="line-height:1.5;"><span style="font-family:Verdana;">Chlorhexidine is a widely used antiseptic agent;however, its bactericidal effect against bacterial endospores is limited. The genus </span><i><span style="font-family:Verdana;">Bacillus</span></i><span style="font-family:Verdana;"> is spore-</span></span><span "="" style="line-height:1.5;"><span style="font-family:Verdana;">forming gram-positive bacteria that are ubiquitously found in the environment and cause opportunistic infection and food poisoning. The susceptibility of bacterial endospores to chlorhexidine was previously evaluated in </span><i><span style="font-family:Verdana;">Bacillus</span></i> <i><span style="font-family:Verdana;">subtilis</span></i><span style="font-family:Verdana;">, but the primary target for disinfection with antiseptic agents, including chlorhexidine, should be harmful strains. We aimed to evaluate the susceptibility of harmful </span><i><span style="font-family:Verdana;">cereus</span></i><span style="font-family:Verdana;"> group including </span><i><span style="font-family:Verdana;">Bacillus</span></i> <i><span style="font-family:Verdana;">cereus</span></i><span style="font-family:Verdana;">, and to compare that with harmless </span><i><span style="font-family:Verdana;">Bacillus</span></i><span style="font-family:Verdana;"> species, containing </span><i><span style="font-family:Verdana;">B.</span></i> <i><span style="font-family:Verdana;">subtilis</span></i><span style="font-family:Verdana;">. We evaluated the susceptibility of the 15 strains of the </span><i><span style="font-family:Verdana;">cereus</span></i><span style="font-family:Verdana;"> group to chlorhexidine in comparison with the 5 other strains, named the </span><i><span style="font-family:Verdana;">subtilis</span></i><span style="font-family:Verdana;"> group in this study. Our results indicated that chlorhexidine exerted a bacteriostatic effect against </span><i><span style="font-family:Verdana;">Bacillus</span></i><span style="font-family:Verdana;<span "="" style="line-height:1.5;"><span style="font-family:Verdana;">Chlorhexidine is a widely used antiseptic agent;however, its bactericidal effect against bacterial endospores is limited. The genus </span><i><span style="font-family:Verdana;">Bacillus</span></i><span style="font-family:Verdana;"> is spore-</span></span><span "="" style="line-height:1.5;"><span style="font-family:Verdana;">forming gram-positive bacteria that are ubiquitously found in the environment and cause opportunistic infection and food poisoning. The susceptibility of bacterial endospores to chlorhexidine was previously evaluated in </span><i><span style="font-family:Verdana;">Bacillus</span></i> <i><span style="font-family:Verdana;">subtilis</span></i><span style="font-family:Verdana;">, but the primary target for disinfection with antiseptic agents, including chlorhexidine, should be harmful strains. We aimed to evaluate the susceptibility of harmful </span><i><span style="font-family:Verdana;">cereus</span></i><span style="font-family:Verdana;"> group including </span><i><span style="font-family:Verdana;">Bacillus</span></i> <i><span style="font-family:Verdana;">cereus</span></i><span style="font-family:Verdana;">, and to compare that with harmless </span><i><span style="font-family:Verdana;">Bacillus</span></i><span style="font-family:Verdana;"> species, containing </span><i><span style="font-family:Verdana;">B.</span></i> <i><span style="font-family:Verdana;">subtilis</span></i><span style="font-family:Verdana;">. We evaluated the susceptibility of the 15 strains of the </span><i><span style="font-family:Verdana;">cereus</span></i><span style="font-family:Verdana;"> group to chlorhexidine in comparison with the 5 other strains, named the </span><i><span style="font-family:Verdana;">subtilis</span></i><span style="font-family:Verdana;"> group in this study. Our results indicated that chlorhexidine exerted a bacteriostatic effect against </span><i><span style="font-family:Verdana;">Bacillus</span></i><span style="font-family:Verdana;

关 键 词：Bacillus cereus Bacillus subtilis  Chlorhexidine Susceptibility 

分 类 号：O17[理学—数学]