An Efficient and Rapid Synthesis of 2-amino-4-arylthiazoles Employing Microwave Irradiation in Water  

作　　者：Kishor S. Jain Jitender B. Bariwal Muthu K. Kathiravan Vikas K. Raskar Gajanan S. Wankhede Nitin A. Londhe Satish N. Dighe 

机构地区：[1]不详

出　　处：《Green and Sustainable Chemistry》2011年第2期35-38,共4页绿色与可持续化学（英文）

摘　　要：A facile, high yielding green chemical synthetic protocol adaptable to the parallel synthesis of a library of potentially bioactive 2-amino-4-arylthiazoles is reported herein. The methodology involves the condensation of various aracyl bromides with N-arylthioureas under MWI using water as solvent, to yield pure products (81%-97%) in very short reaction times (1-20 min).A facile, high yielding green chemical synthetic protocol adaptable to the parallel synthesis of a library of potentially bioactive 2-amino-4-arylthiazoles is reported herein. The methodology involves the condensation of various aracyl bromides with N-arylthioureas under MWI using water as solvent, to yield pure products (81%-97%) in very short reaction times (1-20 min).

关 键 词：Green CHEMICAL Synthesis MWI WATER 2-amino-4-arylthiazoles 

分 类 号：O6[理学—化学]