Sodium-Modified Fluorapatite: A Mild and Efficient Reusable Catalyst for the Synthesis of <i>α,α</i>’-Bis(Substituted Benzylidene) Cycloalkanones under Conventional Heating and Microwave Irradiation  

作　　者：Bahija Mounir Fathallaah Bazi Abddelfetah Mounir Mohamed Zahouily Hamid Toufik 

机构地区：[1]Laboratoire Materiaux, Substances Naturelles, Environnement & Modelisation (LMSNEM), Faculte Polydisciplinaire de Taza,Universite Sidi Mohamed Ben Abdellah, Fes, Maroc [2]Laboratoire de Chimie Analytique et physicochimie des Maté riaux, Faculté des Sciences Ben M’Sik de Casablanca, Université Hassan II, Casablanca, Maroc [3]Higher Institute of Nursing Professions and Health Techniques, Marrakech, Morroco [4]Laboratoire de Maté riaux, Catalyse et Valorisation des Ressources Naturelles, Faculté des Sciences et Techniques de Mohammedia, Université Hassan II, Casablanca, Maroc

出　　处：《Green and Sustainable Chemistry》2018年第2期156-166,共11页绿色与可持续化学（英文）

摘　　要：A versatile and environmentally friendly method for α,α’-bis(substituted ben-zylidene) cycloalkanones has been developed using a heterogeneous catalysis technology. We have synthesized a series of the α,α’-bis(substituted benzylidene) cycloalkanones, a biologically important class of compounds, via the cross aldol condensation between arylaldehydes and cycloketones using sodium-modified fluorapatite (Na/FAP) as a highly efficient solid catalyst under conventional heating in aqueous media and solventless conditions under microwave. Catalyst reuse, ease of separation of the pure product, and high yields are some of the unique features of this process. Shorter reaction times (4 - 7 min) and higher yields (80% - 94%) were achieved under microwave irradiation conditions.A versatile and environmentally friendly method for α,α’-bis(substituted ben-zylidene) cycloalkanones has been developed using a heterogeneous catalysis technology. We have synthesized a series of the α,α’-bis(substituted benzylidene) cycloalkanones, a biologically important class of compounds, via the cross aldol condensation between arylaldehydes and cycloketones using sodium-modified fluorapatite (Na/FAP) as a highly efficient solid catalyst under conventional heating in aqueous media and solventless conditions under microwave. Catalyst reuse, ease of separation of the pure product, and high yields are some of the unique features of this process. Shorter reaction times (4 - 7 min) and higher yields (80% - 94%) were achieved under microwave irradiation conditions.

关 键 词：Green Chemistry α α’-Bis(Substituted Benzylidene) CYCLOALKANONES Microwaves Irradiation Conventional Heating Aqueous Media FLUORAPATITE Activated by SODIUM Nitrate (Na/FAP) 

分 类 号：O6[理学—化学]