Vilsmeier Haack Adducts as Effective Reagents for Regioselective Nitration of Aromatic Compounds under Conventional and Non-Conventional Conditions  

作　　者：Kamatala Chinna Rajanna Mukka Satish Kumar Purugula Venkanna Soma Ramgopal Marri Venkateswarlu 

机构地区：[1]不详

出　　处：《International Journal of Organic Chemistry》2011年第4期250-256,共7页有机化学国际期刊（英文）

摘　　要：Nitration of aromatic Compounds is triggered by Vilsmeier-Haack reagent (DMF/POCl3) or (DMF/SOCl2) in the presence of KNO3 or NaNO2 under conventional and non-conventional conditions. The reactions af- forded corresponding Nitro derivatives in very good yield with high regioselectivity. The results obtained in non-conventional methods (Micro wave irradiation, Grinding, Sonication) are comparable with those ob- tained under conventional conditions, but the reaction times of former conditions are substantially shorter than that of the latter.Nitration of aromatic Compounds is triggered by Vilsmeier-Haack reagent (DMF/POCl3) or (DMF/SOCl2) in the presence of KNO3 or NaNO2 under conventional and non-conventional conditions. The reactions af- forded corresponding Nitro derivatives in very good yield with high regioselectivity. The results obtained in non-conventional methods (Micro wave irradiation, Grinding, Sonication) are comparable with those ob- tained under conventional conditions, but the reaction times of former conditions are substantially shorter than that of the latter.

关 键 词：NITRATION KNO3 or NaNO2 Vilsmeier-Haack REAGENT Microwave Irradiation (MWI) Grinding Sonication 

分 类 号：O6[理学—化学]