Solvent Free Synthesis of α,α-Bis(Substituted-benzylidene)cycloalkanones Using Covalently Anchored Sulfonic Acid on Silica Gel(SiO_(2)-R-SO_(3)H)as an Efficient and Reusable Heterogeneous Catalyst  

作　　者：Azizollah Habibi Enayatollah Sheikhhosseini Mohammadali Bigdeli Saeed Balalaie Elinaz Farrokhi 

机构地区：[1]Faculty of Chemistry,Tarbiat Moallem University,Tehran,Iran [2]Peptide Chemistry Research Center,K.N.Toosi University of Technology,Tehran,Iran

出　　处：《International Journal of Organic Chemistry》2011年第4期143-147,共5页有机化学国际期刊（英文）

摘　　要：We wish to report a mild and efficient Crossed-Aldol reaction for the synthesis of α, ?-bis(substituted-ben- zylidene)cycloalkanones in the presence of catalytic amounts of covalently anchored sulfonic acid onto sil- ica gel under heterogeneous and solvent-free conditions. The present methodology offers several advantages such as excellent yields, simple procedure and work up steps, short reaction times and easy recovery of the catalyst. We have also demonstrated that the catalyst can be reused successfully.We wish to report a mild and efficient Crossed-Aldol reaction for the synthesis of α, ?-bis(substituted-ben- zylidene)cycloalkanones in the presence of catalytic amounts of covalently anchored sulfonic acid onto sil- ica gel under heterogeneous and solvent-free conditions. The present methodology offers several advantages such as excellent yields, simple procedure and work up steps, short reaction times and easy recovery of the catalyst. We have also demonstrated that the catalyst can be reused successfully.

关 键 词：Crossed-Aldol Condensation Heterogeneous Catalysis α α-Bis(substituted-benzylidene)cycloalkanones SiO_(2)-R-SO_(3)H Solvent-Free 

分 类 号：O6[理学—化学]