Phase Transfer Catalysis Improved Synthesis of 3,4-Dihydropyrimidinones  

作　　者：Hela Slimi Khemais Said Younes Moussaoui Ridha Ben Salem 

机构地区：[1]Physical Organic Chemistry Laboratory(UR11ES74),Science Faculty of Sfax,Sfax University,Sfax,Tunisia [2]Science Faculty of Gafsa,Gafsa University,Gafsa,Tunisia

出　　处：《International Journal of Organic Chemistry》2013年第3期96-100,共5页有机化学国际期刊（英文）

基　　金：financial support of the Ministry of Higher Education and Scientific Research of Tunisia.

摘　　要：Various 3,4-dihydropyrimidinones can be prepared via Biginelli reaction in aqueous media by using quaternary ammonium salts of different alkyl groups (C4 and C8) and anions (Cl-?and Br-) as catalysts. The use of quaternary ammonium salts along with longer alkyl chains increases the yield of the Biginelli reaction;however, bromide ammonium salts are less active than the chloride ones.Various 3,4-dihydropyrimidinones can be prepared via Biginelli reaction in aqueous media by using quaternary ammonium salts of different alkyl groups (C4 and C8) and anions (Cl-?and Br-) as catalysts. The use of quaternary ammonium salts along with longer alkyl chains increases the yield of the Biginelli reaction;however, bromide ammonium salts are less active than the chloride ones.

关 键 词：Multicomponent Reaction Biginelli Reaction 3 4-Dihydropyrimidinones Phase-Transfer Catalysis Quaternary Ammonium Salts 

分 类 号：O6[理学—化学]