Synthesis and Spectral Characterization of Novel 2-Pyrazoline and Bis-2-Pyrazoline Containing Quinoline Moiety  

作　　者：Allaoua Kedjadja Abdelmalek Bouraiou Rachid Merdes 

机构地区：[1]Laboratoire de chimie Appliquée, Faculté des Mathématiques et de l’Informatique et des Sciences de la Matière, Université de Guelma, Guelma, Algeria [2]Département de Science de la Matière, Faculté des Science, Université 20 Aout 1955 Skikda, Skikda, Algeria [3]Unité de Recherche de Chimie de l’Environnement et Moléculaire Structurale, Université des Frères Mentouri, Route de Ain El Bey, Constantine, Algeria

出　　处：《International Journal of Organic Chemistry》2018年第1期105-114,共10页有机化学国际期刊（英文）

摘　　要：Eight new compounds containing in their structures substituted quinoline and pyrazole entity were synthesized in good to excellent yield by cyclocondensation reaction of chalcones and hydrazine hydrate. This reaction was conducted in formic acid in presence of BF3·Et2O or in acetic acid. These approaches were extended to bis-chalcones, which delivered functionalized bispyrazolines. The structures of the prepared compounds were confirmed by IR, 1HNMR, 13CNMR and mass spectral analysis.Eight new compounds containing in their structures substituted quinoline and pyrazole entity were synthesized in good to excellent yield by cyclocondensation reaction of chalcones and hydrazine hydrate. This reaction was conducted in formic acid in presence of BF3·Et2O or in acetic acid. These approaches were extended to bis-chalcones, which delivered functionalized bispyrazolines. The structures of the prepared compounds were confirmed by IR, 1HNMR, 13CNMR and mass spectral analysis.

关 键 词：PYRAZOLINE CHALCONE QUINOLINE CYCLOCONDENSATION 

分 类 号：O6[理学—化学]