<i>β</i>-cyclodextrin Covalently Functionalized Single-Walled Carbon Nanotubes: Synthesis, Characterization and a Sensitive Biosensor Platform  

作　　者：Yong Gao Yu Cao Guiling Song Yiming Tang Huaming Li 

机构地区：[1]不详

出　　处：《Journal of Biomaterials and Nanobiotechnology》2011年第4期454-460,共7页生物材料与纳米技术（英文）

摘　　要：In this study, we presented the preparation of β-cyclodextrin (β-CD) covalently functionalized single-walled carbon nanotubes (SWCNTs) and its application in modifying the solid glass carbon electrode (GCE). Cyclic voltammetry (CV) method was employed to evaluate the performance of the modified GCE. Solubility experiment indicated the conjugation of SWCNTs and β-CD, SWCNTs-β-CD with 8 wt% β-CD content could be well dispersed in water. High-resolution transmission electron microscopy (HRTEM) demonstrated that the aggregated SWCNTs bundle were effectively exfoliated to small bundle, even individual tube. The β-CD component was grafted on the side walls as well as tips of SWCNTs, and the grafted β-CD component was not uniformly coated on the surface of SWCNTs. The CV measurements indicated the performance of the GCE modified by SWCNTs-β-CD was better than that of the GCE modified by the hybrid of SWCNTs/β-CD, where ascorbic acid (AA) and uric acid (UA) were selected as a prelimiltary substrate to evaluate it. The enhanced performance of the modified GCE should be ascribed to the integration of the excellent electrocatalytic property of SWCNTs with the inclusion ability of β-CD to analyte molecule.In this study, we presented the preparation of β-cyclodextrin (β-CD) covalently functionalized single-walled carbon nanotubes (SWCNTs) and its application in modifying the solid glass carbon electrode (GCE). Cyclic voltammetry (CV) method was employed to evaluate the performance of the modified GCE. Solubility experiment indicated the conjugation of SWCNTs and β-CD, SWCNTs-β-CD with 8 wt% β-CD content could be well dispersed in water. High-resolution transmission electron microscopy (HRTEM) demonstrated that the aggregated SWCNTs bundle were effectively exfoliated to small bundle, even individual tube. The β-CD component was grafted on the side walls as well as tips of SWCNTs, and the grafted β-CD component was not uniformly coated on the surface of SWCNTs. The CV measurements indicated the performance of the GCE modified by SWCNTs-β-CD was better than that of the GCE modified by the hybrid of SWCNTs/β-CD, where ascorbic acid (AA) and uric acid (UA) were selected as a prelimiltary substrate to evaluate it. The enhanced performance of the modified GCE should be ascribed to the integration of the excellent electrocatalytic property of SWCNTs with the inclusion ability of β-CD to analyte molecule.

关 键 词：SINGLE-WALLED Carbon Nanotubes (SWCNTs) Β-CYCLODEXTRIN (β-CD) Electrochemical Sensor Covalently 

分 类 号：O6[理学—化学]