Synthesis, Characterization, Antibacterial, and Antifungal Activities of Cobalt(II), Nickel(II) and Copper(II) Complexes with 3-thioacetyl-2-amino-1,4-naphthoquinone and 2-benzoyl-3-amino-1,4-naphthoquinone Ligands  

作　　者：Fatma S. M. Hassan Mahmoud Fayez Nadia Abdalla Fatma S. M. Hassan;Mahmoud Fayez;Nadia Abdalla(Chemistry Department, Faculty of Science, Aswan University, Aswan, Egypt;Luxor Company for Water and Wastewater, Luxor, Egypt)

机构地区：[1]Chemistry Department, Faculty of Science, Aswan University, Aswan, Egypt [2]Luxor Company for Water and Wastewater, Luxor, Egypt

出　　处：《Open Journal of Inorganic Non》2020年第4期45-61,共17页无机非金属材料（英文）

摘　　要：<div style="text-align:justify;"> <span style="font-family:Verdana;">The aim of this work is to synthesize, characterize and evaluate the biological activity of 1,4-naphthoquinone derivatives ligands and their metal—Co(II), Ni(II) and Cu(II) chelates. Continuing our work with another derivatives of 1,4-naphthoquinone ligands, this work had been constructed for synthesis of new ligands derived from 1,4-naphthoquinone such as 3-thioacetyl-2-amino-1,4-naphthoquinone and 2-benzoyl-3-amino-1,4-naphthoquinone (L<span style="white-space:nowrap;">¹</span>-L<span style="white-space:nowrap;">²</span>) which characterized on the basis of elemental analysis, electronic, IR, mass, <span style="white-space:nowrap;">¹</span>H-NMR spectral data. The synthesized ligands have been carried out to achieve the coordination behavior towards bi-valent metal ions like cobalt, nickel and copper. The solid chelates of the different ligands were prepared and subjected to analytical techniques such as elemental analyses, spectroscopic techniques including mass, <span style="white-space:nowrap;">¹</span>H-NMR, and IR spectroscopy, and thermal analyses techniques. The chelates were found to have octahedral geometry. The biological activity of the prepared ligands and their binary metals complexes were also screened against different antifungal and antibacterial organisms.</span> </div><div style="text-align:justify;"> <span style="font-family:Verdana;">The aim of this work is to synthesize, characterize and evaluate the biological activity of 1,4-naphthoquinone derivatives ligands and their metal—Co(II), Ni(II) and Cu(II) chelates. Continuing our work with another derivatives of 1,4-naphthoquinone ligands, this work had been constructed for synthesis of new ligands derived from 1,4-naphthoquinone such as 3-thioacetyl-2-amino-1,4-naphthoquinone and 2-benzoyl-3-amino-1,4-naphthoquinone (L<span style="white-space:nowrap;">¹</span>-L<span style="white-space:nowrap;">²</span>) which characterized on the basis of elemental analysis, electronic, IR, mass, <span style="white-space:nowrap;">¹</span>H-NMR spectral data. The synthesized ligands have been carried out to achieve the coordination behavior towards bi-valent metal ions like cobalt, nickel and copper. The solid chelates of the different ligands were prepared and subjected to analytical techniques such as elemental analyses, spectroscopic techniques including mass, <span style="white-space:nowrap;">¹</span>H-NMR, and IR spectroscopy, and thermal analyses techniques. The chelates were found to have octahedral geometry. The biological activity of the prepared ligands and their binary metals complexes were also screened against different antifungal and antibacterial organisms.</span> </div>

关 键 词：1 4-Naphthoquinone Transition Metal Complexes Antibacterial Activity Antifungal Activity 

分 类 号：O62[理学—有机化学]