supported by the National Natural Science Foundation of China (20771068 and 20901048);the PhD Programs Foundation of the Ministry of Education of China (20091401110007)
A new model used to calculate the free energy change of protein unfolding is presented. In this model, proteins are considered to be composed of structural elements. The unfolding of a structural element obeys a two-s...
supported by the National Natural Science Foundation of China(20771068,20901048);the Ph.D Programs Foundation of Ministry of Education of the People’s Republic of China(20091401110007);the Natural Science Foundation of Shanxi Province(2007011024)
Ciliate Euplotes octocarinatus centrin (EoCen) is an EF-hand calcium-binding protein closely related to the prototypical calcium sensor protein calmodulin.The first amino acid of the Ca2+-binding loops found in the EF...
supported by the National Natural Science Foundation of China (20771068 and 20901048);the Ph.D. Programs Foundation of the Ministry of Education of China (20091401110007);the Natural Sci-ence Foundation of Shanxi Province (2010011011-1)
In the current three-state protein unfolding model, the two transitions are considered to be independent and each transition is fitted to a two-state unfolding model. This three-state unfolding process is therefore co...