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CASCADE: 作品数：779被引量：1389H指数：14; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王万龙刘达新董玉德杨华王红星更多>>; 相关机构：中国科学院浙江理工大学广东工业大学清华大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家高技术研究发展计划更多>>

Fe(Ⅲ)-juglone nanoscale coordination polymers for cascade chemodynamic therapy through synergistic ferroptosis and apoptosis strategy: 《Chinese Chemical Letters》2024年第11期413-418,共6页Zhendong Liu Sainan Liu Bin Liu Qi Meng Meng Yuan Chunzheng Yang Yulong Bian Ping'an Ma Jun Lin; financially supported by the National Key Research and Development Program of China(No.2022YFB3503700);the National Natural Science Foundation of China(NSFC,Nos.51929201,52102354,and 52202353);the projects for science and technology development plan of Jilin province(Nos.20220101070JC,20210402046GH,and 20220508089RC)。; Chemodynamic therapy(CDT)relying on the transformation of endogenous hydrogen peroxide(H_(2)O_(2))into cytotoxic hydroxyl radicals(·OH)based on the catalysis of Fenton/Fenton-type reactions exhibits great potentialit...; 关键词：Nanoscale coordination polymers JUGLONE Tumor microenvironment Enhanced chemodynamic therapy Ferroptosis

NIR-triggered on-site NO/ROS/RNS nanoreactor:Cascade-amplified photodynamic/photothermal therapy with local and systemic immune responses activation: 《Opto-Electronic Advances》2024年第6期58-73,共16页Ziqing Xu Yakun Kang Jie Zhang Jiajia Tang Hanyao Sun Yang Li Doudou He Xuan Sha Yuxia Tang Ziyi Fu Feiyun Wu Shouju Wang; the financial support from the National Natural Science Foundation of China (No. 82372019, 82022034, 82173327);Jiangsu Province Natural Science Foundation of China (BK20200032);Double First Class Foundation of China Pharmaceutical University(CPUQNJC22_03); Photothermal and photodynamic therapies(PTT/PDT)hold promise for localized tumor treatment,yet their full potential is hampered by limitations such as the hypoxic tumor microenvironment and inadequate systemic immune ...; 关键词：photothermal therapy photodynamic therapy nitric oxide reactive nitrogen species triple-negative breast cancer immune response NANOREACTOR

Energy,exergy,and economic analysis of compression-absorption cascade refrigeration cycle using different working fluids: 《Energy Storage and Saving》2024年第2期87-95,共9页Yuhan Du Chenhan Chi Xiaopo Wang; supported by the National Natural Science Foundation of China(Grant No.:51936009).; Compression-absorption cascade refrigeration cycle(CACRC)combined with vapor-compression refrigeration and absorption refrigeration cycle attracts great interest due to the less electricity consumption and utilization...; 关键词：Compression-absorption cascade refrigeration cycle Working fluids Economic analysis Multi-objective optimization

Acetylacetone-TiO_(2) Promoted Large Area Compatible Cascade Electron Transport Bilayer for Efficient Perovskite Solar Cells: 《Energy & Environmental Materials》2024年第2期221-228,共8页Hyong Joon Lee Jin Kyoung Park Jin Hyuck Heo Sang Hyuk Im; supported by the National Research Foundation of Korea(NRF)under the Ministry of Science;ICT&Future Planning(Basic Science Research Program[No.2021R1A5A6002853],[No.2022R1A2C3004964],[No.2022R1C1C2008126],[No.2022M3H4A1A03074093]); In designing efficient perovskite solar cells(PSCs),the selection of suitable electron transport layers(ETLs)is critical to the final device performance as they determine the driving force for selective charge extract...; 关键词：ACETYLACETONE large area PEROVSKITE solar cells TiO_(2)

NIR-II light triggered burst-release cascade nanoreactor for precise cancer chemotherapy: 《Bioactive Materials》2024年第3期311-323,共13页Yu-Jing Pan Yang Zhang Biao-Qi Chen Yi Zhao Jin-Yang Wang Chang-Yong Li Da-Gui Zhang Ranjith Kumar Kankala Shi-Bin Wang Gang Liu Ai-Zheng Chen; support from the National Natural Science Foundation of China(NSFC,81971734,32071323,32271410,and 82202330);the National Key Research&Development Program of China(2019YFE0113600);the Science and Technology Projects in Fujian Province(2022FX1,2023Y4008);the Program for Innovative Research Team in Science and Technology in Fujian Province University,and the Scientific Research Funds of Huaqiao University(23BS113).; The current strategy of co-delivering copper ions and disulfiram(DSF)to generate cytotoxic CuET faces limitations in achieving rapid and substantial CuET production,specifically in tumor lesions.To overcome this chall...; 关键词：Ultrasmall Cu_(2-x)Se nanoparticles High surface activity NANOREACTOR Phase change materials Precise chemotherapy

基于共价有机框架的纳米酶用于级联放大反应协同治疗癌症被引量：1: 《Science China Materials》2023年第10期4079-4089,共11页冯杰孔斐岳万胜于浩何梓良翟亚男董育斌; supported by the National Natural Science Foundation of China(21971153 and 22371172);the Major Basic Research Projects of Shandong Provincial Natural Science Foundation(ZR2020ZD32);Taishan Scholars Climbing Program of Shandong Province,China Postdoctoral Science Foundation(2020M682225);the Natural Science Foundation of Shandong Province(ZR202102280580 and ZR202102210262)。; 在肿瘤微环境中,过氧化氢(H_(2)O_(2))的浓度受限,导致模拟过氧化物酶(POD)介导的单一催化治疗无法完全消除肿瘤.为了克服这个问题,我们将2,2’氮基-双(3-乙基苯并噻唑-6-磺酸)(ABTS)负载到具有模拟过氧化物酶活性的铁卟啉基共价有机框...; 关键词：nanozymes nanoscale covalent organic frameworks cascade-amplified glutathione depletion synergistic cancer therapy

Cascade excitation of vortex motion and reentrant superconductivity in flexible Nb thin films: 《Chinese Physics B》2023年第4期613-621,共9页张丽萍徐祖雨黎晓杰张旭秦明阳张若舟徐娟程文欣袁洁王华兵 Alejandro V.Silhanek 朱北沂苗君金魁; Project supported by the National Key Basic Research Program of China(Grant Nos.2021YFA0718700,2018YFB0704102,2017YFA0303003,2017YFA0302902,2016YFA0300301,and 2021YFA0718802);the National Natural Science Foundation of China(Grant Nos.11927808,11834016,118115301,119611410,11961141008,61727805;11961141002);the Key Research Program of Frontier Sciences,Chinese Academy of Sciences(CAS)(Grant Nos.QYZDB-SSW-SLH008 and QYZDY-SSW-SLH001);CAS Interdisciplinary Innovation Team,the Strategic Priority Research Program(B)of CAS(Grant Nos.XDB25000000and XDB33000000);the Beijing Natural Science Foundation(Grant No.Z190008);the Key-Area Research and Development Program of Guangdong Province,China(Grant No.2020B0101340002);the support from the China Postdoctoral Science Foundation(Grant No.2022M711497)。; High quality Nb films were successfully prepared on both flexible polyimide(PI)and rigid Al2O3substrates and their transport properties were systematically studied at various applied currents,external magnetic fields,...; 关键词：vortex dynamics flexible superconducting films transport properties superconducting films

Real-time in situ observation of P53-mediated cascade activation of apoptotic pathways with nucleic acid multicolor fluorescent probes based on symmetrical gold nanostars: 《Nano Research》2023年第4期5391-5400,共10页Chenbiao Li Peifang Chen Xiaoyuan Ma Xichi Lin Shan Xu Sobia Niazi Zhouping Wang; the financial support from the Jiangsu Agriculture Science and Technology Innovation Fund(No.CX(19)2005);the Social Development Fund Project of Wuxi(No.N20201001).; T-2 toxin,one of the most dangerous natural pollutants,induces apoptosis through multiple pathways.Amongst,P53 mediated apoptosis pathway,an important collection of molecules,plays a key role in cell vital activity.Re...; 关键词：nucleic acid multicolor fluorescent probe symmetric gold nanostars T-2 toxin P53 mediated apoptosis pathway living cells imaging

A microfluidic surface-enhanced Raman scattering(SERS) sensor for microRNA in extracellular vesicles with nucleic acid-tyramine cascade amplification被引量：2: 《Chinese Chemical Letters》2022年第4期2101-2104,共4页Yue Zhao Xiaoxing Fang Min Bai Jin Zhang Huahang Yu Feng Chen Yongxi Zhao; supported by the National Natural Science Foundation of China (Nos. 31671013, 22004096, 21874105and 21705124);the China Postdoctoral Science Foundation (Nos.2019M663658 and 2020T130096ZX);the Natural Science Basic Research Program of Shaanxi (Nos. 2020JQ-020, 2020JQ-021 and2018JC-001);the Fundamental Research Funds for the Central Universities (No. xzy012020034);“Young Talent Support Plan” of Xi’an Jiaotong University。; Exosomal micro RNA(mi RNA) is an ideal candidate of noninvasive biomarker for the early diagnosis of cancer. Sensitive and accurate sensing of abnormal exosomal mi RNA plays essential role for clinical promotion due t...; 关键词：Microfluidic chips Surface-enhanced Raman scattering(SERS) EXOSOME Tyramide signal amplification Nucleic acid amplification

Organelle-inspired supramolecular nanomedicine to precisely abolish liver tumor growth and metastasis被引量：2: 《Bioactive Materials》2022年第3期120-133,共14页Jie Zhan Yuhan Wang Shaodan Ma Qin Qin Ling Wang Yanbin Cai Zhimou Yang; We thank Prof.Chihua Fang from Zhujiang hospital of Southern Medical University for sharing the HepG2-luci cells and the c(RGDfC)peptide.We acknowledge the financial support from the National Science Fund for Distinguished Young Scholars(31825012);National Natural Science Foundation of China(21875116,31961143004,81921004,31900952,51973090);Tianjin Science Fund for Distinguished Young Scholars(17JCJQJC44900);Guangdong Basic and Applied Basic Research Foundation(2018A030313446,2019A1515011706,2019A1515110638);and the China Postdoctoral Science Foundation(BX20190149,2019M662972).; Organelles are responsible for the efficient storage and transport of substances in living systems.A myriad of extracellular vesicles(EVs)acts as a bridge to exchange signaling molecules in cell-cell communication,and...; 关键词：SELF-ASSEMBLY Organelle-mimicking Nuclear delivery Dynamic cascade process Cancer therapy

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