Financial support:This research was supported by the National Natural Science Foundation of China(81803443,and 81903551);Zhejiang Province Natural Science Foundation(LQ19H300001);Wenzhou Municipal Science and Technology Bureau(Y20180180);Xinmiao Talent Program of Zhejiang Province(Grant No.2021R413073);and Excellent Young Scientist Training Program fund from Wenzhou Medical University.
Reprogramed cellular metabolism is one of the most significant hallmarks of cancer.All cancer cells exhibit increased demand for specific amino acids,and become dependent on either an exogenous supply or upregulated d...