POLY-L-LYSINE

作品数：24被引量：46H指数：4
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相关作者：张海燕石嵘马文丽张宝李凌更多>>
相关机构：中国人民解放军第一军医大学广州军区广州总医院青岛科技大学更多>>
相关期刊：《Asian Journal of Pharmaceutical Sciences》《Science Bulletin》《Military Medical Research》《Food Quality and Safety》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金上海市自然科学基金更多>>
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Biodegradable cationic e-poly-L-lysine-conjugated polymeric nanoparticles as a new effective antibacterial agent
《Science Bulletin》2015年第2期216-226,I0002,共12页赵瑞芳 王海 季天骄 Greg Anderson 聂广军 赵宇亮 
supported by the National Basic Research Program of China(2012CB934000,2011CB933400);the National Natural Science Foundation of China(31325010,21277037)
Biocompatible and biodegradable ε-poly-L- lysine （EPL）/poly （ε-caprolactone） （PCL） copolymer was designed and synthesized. The amphiphilic EPL-PCL copolymer could easily self-assembled into monodispersed nanop...
关键词：EPL-PCL copolymers Biodegradable cationic nanoparticles Broad-spectrum antibacterial activity Disruption of bacterial walls/membranes Cell invagination 
A novel nonviral nanoparticle gene vector: Poly-L-lysine- silica nanoparticles被引量：9
《Chinese Science Bulletin》2002年第8期654-658,共5页Shiguo Zhu Hongbin Lu Juanjuan Xiang Ke Tang Bicheng Zhang Ming Zhou Chen Tan Guiyuan Li 
This work was supported by the National High Technology R&D Project of China (Grant No. 102-10-01-05);the Special Funds for Major State Basic Research of China (Grant No. 1998051008);the Key Program Funds of the Ministry of Education (Grant No. 2000-15
DNA delivery is a core technology for gene structure and function research as well as clinical settings. The ability to safely and efficiently targeted transfer foreign DNA into cells is a fundamental goal in biotechn...
关键词：NANOPARTICLE gene vector SILICA NANOPARTICLES poly-L-lysine-silica NANOPARTICLES synthesis DNA delivery cell transfection. 
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