HOMODIMERIZATION

作品数：5被引量：7H指数：2
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相关领域：生物学更多>>
相关作者：曲宇杰赵阳曹雪松刘国富更多>>
相关机构：聊城大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《Neuroscience Bulletin》《中国生物学文摘》《Cell Research》更多>>
相关基金：国家自然科学基金更多>>
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The C terminus of DJ-1 determines its homodimerization, MGO detoxification activity and suppression of ferroptosis被引量：2
《Acta Pharmacologica Sinica》2021年第7期1150-1159,共10页Li Jiang Xiao-bing Chen Qian Wu Hai-ying Zhu Cheng-yong Du Mei-dan Ying Qiao-jun He Hong Zhu Bo Yang Ji Cao 
This work was supported by grants from National Science Technology Major Project"Key New Drug Creation and Manufacturing Program",China(2018ZX09711002 to HZ);the National Natural Science Foundation of China(No.81773757 to MDY;No.81402951 to JC);and Zhejiang Medical and Health Science and Technology Program(No.2020384517 to CYD).
DJ-1 is a multifunctional protein associated with cancers and autosomal early-onset Parkinson disease. Besides the well- documented antioxidative stress activity, recent studies show that DJ-1 has deglycation enzymati...
关键词：DJ-1 C terminus HOMODIMERIZATION methylglyoxal(MGO)detoxification deglycation ferroptosis HEK293T cells DJ-1−/−mouse embryonic fibroblast cells 
Cysteine residues 87 and 320 in the amino terminal domain of NMDA receptor GluN2A govern its homodimerization but do not influence GluN2A/GluN1 heteromeric assembly被引量：2
《Neuroscience Bulletin》2013年第6期671-684,共14页Xiao-Min Zhang Xin-You Lv Yang Tang Li-Jun Zhu Jian-Hong Luo 
supported by grants from the National Basic Research Development Program of China(2010CB912002);the National Natural Science Foundation of China(30730038 and 81171164)
N-Methyl-D-aspartate receptors（NMDARs） play a central role in various physiological and pathological processes in the central nervous system.And they are commonly composed of four subunits,two GluN1 subunits and two...
关键词：N-methyl-D-aspartate receptor amino terminal domain HOMODIMERIZATION heteromeric assembly 
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