supported by the CAMS Innovation Fund for Medical Sciences(CIFMS,Nos.2021-I2M-1-069,2022-12M-2-002);Beijing Municipal Natural Science Foundation,China(No.7222259)。
Schisandrin A is a natural dibenzocyclooctene lignan with potent neuroprotective activity.However,the specific mechanisms or direct target proteins have not been clarified up to now.In this study,we designed and synth...
(S)-Dimethyl-4, 4′-dimethoxy-5, 6, 5′, 6′-dimethenedioxy-biphenyl-2, 2′-dicarbonylatewas synthesized in reasonable yield through a series of reactions, including chiral oxazoline-mediated asymmetric Ullmann coupli...