Supported by the National Natural Science Foundation of China under Grant Nos 11247010,11175055,11475053 and 11347017;the Natural Science Foundation for Distinguished Young Scholars of Hebei Province under Grant No C2015202340;the Natural Science Foundation of Hebei Province under Grant Nos C2012202079 and C201400305;the Scientific Innovation Fund for Excellent Young Scientists of Hebei University of Technology under Grant No 2015010
To accomplish their functions, proteins have to achieve different conformations accompanied by conformational transitions. However, the relationship between the preference of amino acids and the stability of the secon...