supported by National Natural Science Foundation of China [No.81572930];Beijing Science and Technology Plan [No.D171100002617004];the Scientific Research Foundation of Graduate School of Harbin Medical University [YJSCX2017-63HYD].
Background p50-associated cyclooxygenase-2 extragenic RNA(PACER)is a recently identified antisense long non-coding RNA(lncRNA)located on the upstream of the promoter region of cyclooxygenase-2(COX-2).Preliminary studi...