supported by the National Natural Science Foundation of China[grant number 81872463 and 81930072];Special Support Program of Sun Yat-sen University Cancer Center[grant number 16zxtzlc06];Key-Area Research and Development Program of Guangdong Province[grant number 2019A1515012045 and 2019B020230002];Health&Medical Collaborative Innovation Project of Guangzhou City,China[grant number 201803040003];Science and Technology Program of Guangzhou,China,[grant number 201607010199];Innovation Team Development Plan of the Ministry of Education(No.IRT_17R110);Overseas Expertise Introduction Project for Discipline Innovation(111 Project,B14035);Natural Science Foundation of Guang Dong Province(No.2017A030312003).
Background:Oral cavity(OC),oropharyngeal(OP),hypopharyngeal(HP),and laryngeal(LA)squamous cell carcinoma(SCC)have a high incidence of regional lymph node metastasis(LNM).Elective irradiation for clinically node-negati...