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Garlic-derived compound S-allylmercaptocysteine inhibits hepatocarcinogenesis through targeting LRP6/Wnt pathway被引量:9
《Acta Pharmaceutica Sinica B》2018年第4期575-586,共12页Jia Xiao Feiyue Xing Yingxia Liu Yi Lv Xiaogang Wang Ming-Tat Ling Hao Gao Songying Ouyang Min Yang Jiang Zhu Yu Xia Kwok-Fai So George L.Tipoe 
supported by Foundation of Pearl River Science and Technology New Star (grant number 201506010087);Basic Research Fund of Shenzhen City (JCYJ20150402111430633) to Jia Xiao;Health Medical Research Fund (HMRF,No. 12133881);General Research Fund and Small Project Funding;University Research Committee,The University of Hong Kong. to George L.Tipoe;National Natural Science Foundation of China (No. 81570552);National Program on Key Basic Research Project of China (973 Program,2014CB542205);Funds of Leading Talents of Guangdong (2013);Programme of Introducing Talents of Discipline to Universities (B14036) to Kwok-Fai So;National Health and Medical Research Council (1031221 & 1031228) to Ming-Tat Ling
Whether and how garlic-derived S-allylmercaptocysteine(SAMC) inhibits hepatocellular carcinoma(HCC) is largely unknown. In the current study, the role of low-density lipoprotein receptor(LDLR)-related protein 6(LRP6) ...
关键词:S-allylmercaptocysteine HCC WNT LRP6 Human Nude mice 
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