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Extensive expansion of the chemical diversity of fusidane-type antibiotics using a stochastic combinational strategy被引量：1
《Acta Pharmaceutica Sinica B》2021年第6期1676-1685,共10页Xiaojun Song Jianming Lv Zhiqin Cao Huiyun Huang Guodong Chen Takayoshi Awakawa Dan Hu Hao Gao Ikuro Abe Xinsheng Yao 
financially supported by grants from National Key Research and Development Program of China (2018YFA0903200 and 2018YFA0903201);the National Natural Science Foundation of China (31870032, 81925037, 31761143016, 31670036 and 31800021);the 111 Project of Ministry of Education of the People’s Republic of China (B13038);Chang Jiang Scholars Program (Young Scholar) from the Ministry of Education of China (Hao Gao, 2017);National High-level Personnel of Special Support Program (2017RA2259, China);the Guangdong Natural Science Funds for Distinguished Young Scholar (2019B151502014, China);Guangdong Science and Technology Planning Project (2020A0505100041, China);Guangdong Special Support Program (2016TX03R280, China);Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program (2017BT01Y036, China);K. C. Wong Education Foundation (Hao Gao, 2016, China);Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan (JSPS KAKENHI Grant Number JP16H06443, JP20KK0173, and JP20H00490)。
Fusidane-type antibiotics,represented by helvolic acid,fusidic acid and cephalosporin P1,are fungi-derived antimicrobials with little cross-resistance to commonly used antibiotics.Generation of new fusidane-type deriv...
关键词：Fusidane-type antibiotics Combinational biosynthesis TRITERPENOIDS Fungi Tailoring enzymes 
QTL-allele matrix detected from RTM-GWAS is a powerful tool for studies in genetics, evolution, and breeding by design of crops被引量：2
《Journal of Integrative Agriculture》2020年第5期1407-1410,共4页HE Jian-bo GAI Jun-yi 
supported by the National Natural Science Foundation of China(31701447);the National R&D Program of China(2016YFD0100201,2016YFD0100304,2017YFD0100500,and 2017YFD0102002);the 111 Project of Ministry of Education,China(B08025);the Program for Changjiang Scholars and Innovative Research Team in University,China(PCSIRT_17R55);the earmarked fund for China Agriculture Research System(CARS-04);the Fundamental Research Funds for the Central Universities,China(KYT201801);the Jiangsu Collaborative Innovation Center for Modern Crop Production,China。
The plant germplasm resources harboring abundant genetic variations are necessary wealth in developing new cultivars adapted to various geographic and seasonal conditions.Unraveling the complex genetic architecture un...
关键词：breeding GERMPLASM CROPS 
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