PHOTOSWITCH

作品数:16被引量:13H指数:2
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Photo-Modulation of Gene-Editing Enzymes CRISPR/Cas9 with Bifunctional Small-Molecule Ligands被引量:2
《Chinese Journal of Chemistry》2023年第24期3639-3644,共6页Yidan Zhang Yixin Zhang Lili Han Qiaoling Che Jiawei Tan Peng Zou Yiyun Chen 
supported by the National Natural Science Foundation of China(22337005,22277133,91753126);the Youth Innovation Promotion Association(CAS 2023266);the CAS Interdisciplinary Innovation Team(JCTD-2020-16);the Program of Shanghai Academic/Technology Research Leader(21XD1424700).
The control of protein functions with light is valuable for spatiotemporal probing of biological systems.Current small-molecule photo-modulation methods include the light-induced uncaging of inhibitors and chromophore...
关键词:Gene-editing Small-molecule ligands Enzyme modulation DNA cleavage PHOTOSWITCH Inhibitors 
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